Combining cognitive restructuring and mindfulness for anxiety and depression treatment

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial evaluates the effects of combining cognitive restructuring and detached mindfulness, two components of cognitive behavioral therapy, on patients with anxiety and depression. It aims to explore the effectiveness of these treatments both individually and in combination, while also examining demographic and clinical factors that may influence outcomes. The study is designed as a randomized controlled trial, ensuring rigorous assessment of the treatment effects. Participants will engage in online therapy sessions, allowing for a flexible and accessible approach to mental health care.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Age ≥ 18 years.
2. A diagnosis of an anxiety disorder (generalized anxiety disorder, social anxiety disorder, or panic disorder with or without agoraphobia) and/or mild to moderate major depressive disorder (MDD) according to DSM-5 (American Psychiatric Association, 2022).
3. Danish language proficiency.
4. Ability and willingness to give informed consent.
5. No or stable antidepressant/antianxiety medication (i.e., same dosage for ≥ 8 weeks).
6. Access to either a smartphone, tablet, or computer with video camera.

Exclusion Criteria:

1. Severe depression deemed to require more intense psychotherapy or medication.
2. Persistent depressive disorder (i.e., depressive symptoms have persisted for 2 years or more).
3. Non-stabilized medication (see above).
4. Currently receiving other psychotherapy or counseling.
5. Not capable of participating online.
6. Lack of Danish proficiency.
7. A history of bipolar disorder.
8. Current or past psychosis.
9. Substance abuse or dependence judged to require treatment.
10. Suicide risk requiring immediate hospitalization.

Where it's running

• Department of Psychology and Behavioral Sciences
  Aarhus, Denmark Recruiting

Study contacts

• Principal investigator: Caroline Nørskov, MSc — University of Aarhus
• Study coordinator: Caroline Nørskov, MSc
• Email: cn@psy.au.dk
• Phone: +4587150193

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.