Combining brain stimulation with cognitive-motor training for stroke recovery
The Effect of Dual-task Training Combined With tDCS on Cognitive-motor Interference and Related Brain Activity in Stroke Patients
NA · The Hong Kong Polytechnic University · NCT06769672
This study is testing if combining brain stimulation with special training can help stroke patients improve their ability to walk and do other tasks at the same time.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 72 (estimated) |
| Ages | 50 Years and up |
| Sex | All |
| Sponsor | The Hong Kong Polytechnic University (other) |
| Locations | 1 site (Hong Kong) |
| Trial ID | NCT06769672 on ClinicalTrials.gov |
What this trial studies
This study evaluates the effects of transcranial direct current stimulation (tDCS) combined with dual-task cognitive-motor training on stroke patients. It focuses on how this intervention can improve dual-task performance during activities like walking and pedaling, which are essential for community ambulation. The study aims to understand the changes in brain activity associated with these tasks and how they relate to cognitive-motor interference experienced by stroke survivors. By addressing these challenges, the research seeks to enhance post-stroke recovery and quality of life.
Who should consider this trial
Good fit: Ideal candidates are community-dwelling individuals aged 50 or older who have experienced a stroke more than 6 months prior and can follow instructions.
Not a fit: Patients with other neurological disorders, significant comorbidities, or contraindications to the interventions will not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could significantly improve walking and cognitive performance in stroke patients, facilitating better reintegration into the community.
How similar studies have performed: While the combination of tDCS and cognitive-motor training is a relatively novel approach, emerging evidence suggests potential benefits in similar interventions for stroke rehabilitation.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * a diagnosis of stroke, stroke onset of more than 6 months, * aged 50 or more, * capable of following verbal and visual instructions, * having a Montreal Cognitive Assessment score ≥ 22, * able to walk for 10 meters with/without a mobility aid, * community-dwelling, unilateral stroke Exclusion Criteria: * neurological disorders, gait-precluding pain or comorbidity, * receiving any formal rehabilitation training, * contraindications to exercise (e.g., unstable angina), * contraindications to fNIRS, MRI, and tDCS (e.g., brain skin injury, pacemaker, metal implants in the brain), * history of seizure or epilepsy, * color blindness. * unable to walk with/without a mobility aid while responsing stimulus by the remote control
Where this trial is running
Hong Kong
- The Hong Kong Polytechnic University — Hong Kong, Hong Kong (RECRUITING)
Study contacts
- Study coordinator: Prof. Marco PANG
- Email: Marco.Pang@polyu.edu.hk
- Phone: +852 2766 7156
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Stroke, Cortical Excitability, Dual-task training, Cognitive-motor interference, tDCS