Combining Articaine and Dexmedetomidine for Pain Relief in Surgery
A Comparative Study Between Articaine Alone Versus Articaine Plus Dexmedetomidine for Ambulatory Orthopedic Surgery Under Supraclavicular Block
This study tests if combining a local anesthetic called articaine with a medication called dexmedetomidine can help adults having upper limb surgery feel less pain and recover movement faster.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 66 (estimated) |
| Ages | 18 Years to 60 Years |
| Sex | All |
| Sponsor | Benha University Academic / other |
| Locations | 1 site (Banhā, Qalyubia Governorate) |
| Trial ID | NCT06423859 on ClinicalTrials.gov |
What this trial studies
This study investigates the effectiveness of adding dexmedetomidine to articaine, a local anesthetic, to enhance the duration of sensory and motor block during upper limb surgeries. Articaine is known for its rapid action and lower neurotoxicity compared to other anesthetics. The study aims to determine if this combination can provide adequate pain relief while allowing for early recovery of motor function, which is crucial for initiating physiotherapy post-surgery. Participants will be adults aged 18-60 undergoing specific surgical procedures lasting less than 90 minutes.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18-60 scheduled for upper limb surgery below the midhumerus with a procedure duration of less than 90 minutes.
Not a fit: Patients with allergies to local anesthetics, those with ASA III and IV classifications, or individuals on anticoagulant medications may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could lead to improved pain management and quicker recovery times for patients undergoing upper limb surgeries.
How similar studies have performed: Previous studies have shown success in enhancing analgesia by adding dexmedetomidine to other local anesthetics, but this specific combination with articaine is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * aged 18-60 years planned for upper limb surgery below the midhumerus with an expected time of less than 90 min usually under tourniquet. Exclusion Criteria: * allergies to local anesthetic, * those with ASA III and IV, * patients who refuse to participate, * uncooperative patients, * patients who have infection at the site of injection, * patients who have bleeding disorder, and patients on anticoagulant drugs.
Where this trial is running
Banhā, Qalyubia Governorate
- Samar Rafik Mohamed Amin — Banhā, Qalyubia Governorate, Egypt (Recruiting)
Study contacts
- Study coordinator: Samar R Amin, MD
- Email: samar.rafik@gmail.com
- Phone: +201287793991
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.