Combining a new drug with an antioxidant for early dementia treatment

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial investigates the effects of a combination treatment involving DAOIB, an NMDA-enhancing agent, and an antioxidant in patients with early-stage dementia, specifically Alzheimer's disease and mild cognitive impairment. The study aims to determine if this combined approach can improve cognitive function more effectively than using DAOIB alone. Participants will be assessed based on their cognitive status and will receive either the combination treatment or a placebo. The trial is designed to provide insights into the potential benefits of dual therapy in early dementia.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Clinical diagnosis of Alzheimer's disease or mild cognitive impairment
* MMSE between 10-26
* CDR 1 or 0.5

Exclusion Criteria:

* Hachinski Ischemic Score \> 4
* Substance abuse/dependence
* Parkinson disease, epilepsy, dementia with psychotic features
* Major depressive disorder
* Major physical illnesses
* Severe visual or hearing impairment

Where it's running

• Chang Gung Memorial Hospital
  Kaohsiung City, Taiwan Recruiting

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.