Combined screening for gastrointestinal tumors

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to evaluate the feasibility and health economic benefits of combined screening methods for gastrointestinal tumors, including esophagus, stomach, and colorectal cancers. Participants aged 45 to 70 will undergo a series of tests, including gastroscopy, colonoscopy, and various genetic and risk factor assessments. The study will compare outcomes between two groups: one receiving comprehensive screening and another with limited testing, with a follow-up period of 10 years to observe health outcomes.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* 1\. Subjects were 45 to 70 years old when enrolled 2. Willing and able to sign informed consent

Exclusion Criteria:

* 1\. History of any type of malignancy 2. Previous resection of esophagus, stomach or colorectal 3. Received gastrointestinal endoscopy such as colonoscopy and gastroscopy in recent 5 years 4. Have received fecal occult blood test and fecal DNA test in the past 1 year. 5. Contraindications to endoscopy. 6. Warning symptoms of digestive tract tumors, including:

  1. Difficulty swallowing, choking or halting feeling when eating recently
  2. Recent esophageal foreign body sensation or swallowing pain
  3. Recent long-term loss of appetite and appetite
  4. Recent and prolonged symptoms of indigestion (including acid reflux, heartburn, abdominal grumbling, burping, nausea or premature satiety, etc.)
  5. Recent symptoms of abdominal mass, abdominal pain, vomiting or hematemesis
  6. It was medically diagnosed as iron deficiency anemia
  7. Recent changes in hematochezia, black stool or stool character and frequency
  8. Recent symptoms of perianal discomfort (including soreness, itching, lumps, prolapse or other discomfort)
  9. Unexplained weight loss (more than 10% of base body weight) in the past 6 months Step 7 Get pregnant 8. There are other serious comorbiditions that reduce screening benefits (including severe lung disease, advanced kidney disease, advanced liver disease, severe heart failure, etc.)

Where it's running

• Gaoyao District People's Hospital
  Zhaoqing, Guangzhou, China Recruiting

Study contacts

• Study coordinator: rong zheng
• Email: zhengrong4956@163.com
• Phone: 19829758242

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.