Combined IV plus inhaled anesthesia versus inhaled anesthesia alone for recovery after gynecologic surgery

Effects of Combined Intravenous-Inhalational Anesthesia Versus Inhalational Anesthesia on Postoperative Recovery in Gynecological Operations: A Comparison Based on QoR-15 Scores

NA · Sakarya University · NCT07506798

This test will see if adding intravenous anesthesia to inhaled anesthesia helps adults aged 18–65 recover better after elective gynecologic surgery.

Quick facts

PhaseNA
Study typeInterventional
Enrollment100 (estimated)
Ages18 Years to 65 Years
SexAll
SponsorSakarya University (other)
Locations1 site (Sakarya)
Trial IDNCT07506798 on ClinicalTrials.gov

What this trial studies

One hundred adults (ages 18–65) classified ASA I–III undergoing elective gynecologic procedures at Sakarya University Training and Research Hospital will receive either combined intravenous-inhalational anesthesia or inhalational anesthesia alone. Patients will complete the QoR-15 questionnaire before surgery and again on postoperative days 1 and 2, while intraoperative data will be collected from anesthesia records. The primary outcome is the QoR-15 recovery score, which covers physical comfort, pain, emotional state, psychological support, and ability to perform daily activities. The trial compares postoperative recovery quality between the two anesthesia approaches.

Who should consider this trial

Good fit: Adults aged 18–65 with ASA I–III undergoing elective gynecologic surgery at Sakarya University who can provide informed consent and complete the QoR-15 are eligible.

Not a fit: Patients with severe comorbidities beyond ASA III, advanced neurological/cognitive impairment, emergency surgeries, or known allergies to the anesthetic drugs used are unlikely to benefit or be eligible.

Why it matters

Potential benefit: If successful, the combined anesthesia approach could improve immediate postoperative comfort and faster return to daily activities after gynecologic surgery.

How similar studies have performed: Prior comparisons of combined intravenous-inhalational versus inhalational anesthesia have shown mixed results, with some studies reporting modest improvements in recovery metrics but no consistent superiority.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. Patients aged 18-65 years
2. Scheduled for elective gynecologic surgery at Sakarya University Faculty of Medicine Training and Research Hospital
3. Classified as ASA I-III
4. Able to understand and complete the QoR-15 questionnaire
5. Provided written informed consent

Exclusion Criteria:

1. Severe comorbidities (beyond ASA III)
2. Patients with advanced neurological disease or cognitive impairment
3. Known allergy to anesthetic drugs used in the study
4. Classified as ASA IV-V
5. Refusal to participate in the study
6. Emergency or urgent surgery

Where this trial is running

Sakarya

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Gynecologic Surgery, Postoperative Recovery, Anesthesia

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.