Combined endurance training for improving daily activities in COPD patients
Official title: Effect of Combined Upper and Lower Extremity Endurance Training Versus Lower Extremity Training Alone on ADL and Walking in COPD Patients
Run by Istituti Clinici Scientifici Maugeri SpA · NCT05708443 · Data updated 2026-11-12
This study is testing if combined upper and lower body endurance training can help people with COPD do daily activities better and walk more easily.
Quick facts
| Study type | Interventional |
|---|---|
| Sex | All |
| Enrollment | 36 (estimated) |
| Sponsor | Istituti Clinici Scientifici Maugeri SpA Academic / other |
| Locations | 3 sites (Lumezzane, Brescia and 2 other locations) |
| Status | Recruiting |
| Started | January 10, 2023 |
| Main results expected | February 28, 2027 |
| Study ends | June 30, 2027 |
| Registry record updated | June 24, 2026 |
| Trial ID | NCT05708443 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are individuals diagnosed with GOLD class 2-3 COPD who can walk and climb stairs independently.
✕Probably not a fit
Patients with severe comorbidities, cognitive impairments, or those requiring long-term oxygen therapy may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study evaluates the effects of combined upper and lower limb endurance training on activities of daily living (ADL) and walking ability in patients with Chronic Obstructive Pulmonary Disease (COPD). The intervention includes pulmonary rehabilitation that focuses on enhancing exercise tolerance and reducing symptoms such as dyspnea and fatigue. Participants will be divided into groups receiving either lower limb training or combined upper and lower limb training to assess the additional benefits of the latter. The study aims to improve the quality of life and functional capacity of COPD patients through structured exercise regimens.
Why it matters
Potential benefit: If successful, this approach could significantly enhance the ability of COPD patients to perform daily activities and improve their overall quality of life.
How similar studies have gone: Previous studies have shown positive outcomes with similar rehabilitation approaches, indicating potential for success in this study.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * GOLD class 2-3 COPD * Forced Expiratory Volume in the first second (FEV1) between 30% and 70% of the predicted value * ability to walk and climb stairs without assistance * stable clinical condition (pH \> 7.35) Exclusion Criteria: * chronic respiratory insufficiency on long-term oxygen therapy (LTOT) * severe orthopedic, neurological or cardiological comorbidities * cognitive impairment * recent exacerbation (within 15 days) requiring a change in therapy * presence of lung disease other than COPD * terminality
Where it's running
-
ICS Maugeri IRCCS, Respiratory rehabilitation of the Institute of Lumezzane
Lumezzane, Brescia, Italy Recruiting -
ICS Maugeri IRCCS, Respiratory rehabilitation of the Institute of Montescano
Montescano, Pavia, Italy Not yet recruiting -
ICS Maugeri IRCCS, Respiratory rehabilitation of the Institute of Tradate
Tradate, Varese, Italy Completed
Study contacts
- Study coordinator: Mara Paneroni, MSc, PT
- Email: mara.paneroni@icsmaugeri.it
- Phone: 0039+030+8253
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.