Collection of samples and data for severe drug reactions

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to gather clinical data and biological samples from patients experiencing severe cutaneous adverse reactions, such as Stevens-Johnson syndrome and Lyell syndrome. Conducted at the dermatology department of Henri Mondor Hospital in France, the study will involve collecting skin biopsies, blood samples, and other biological materials to enhance understanding of the immunological and genetic factors involved in these drug reactions. The collected data will support future research aimed at improving treatment and prevention strategies for affected patients.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patient ≥ 18 y-old
* Severe cutaneous drug reaction (AGEP, DRESS, SJS/TEN, generalized bullous fixed drug eruption), drug-induced IgA bullous dermatosis, maculopapular exanthema, erythema multiforme
* Signed consent
* Social security affiliation

Exclusion Criteria:

* Patients law protection

Where it's running

• Henri Mondor
  Créteil, France Recruiting

Study contacts

• Principal investigator: Saskia Oro, MD — Aphp
• Study coordinator: Saskia Oro, MD
• Email: saskia.oro@aphp.fr
• Phone: 0149812536

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.