Collection of nasal samples from healthy volunteers

Establishment of a Biobank of Nasal Epithelium Samples From Healthy Volunteers

Observational National Institutes of Health Clinical Center (CC) · NCT06120244

This study is collecting nasal samples from healthy adults to help researchers learn more about respiratory diseases and develop new treatments.

Quick facts

Study typeObservational
Enrollment120 (estimated)
Ages18 Years to 99 Years
SexAll
SponsorNational Institutes of Health Clinical Center (CC) NIH
Locations1 site (Hamilton, Montana)
Trial IDNCT06120244 on ClinicalTrials.gov

What this trial studies

This observational study aims to collect nasal epithelium samples from healthy volunteers to establish a biobank for future research on respiratory diseases. Participants aged 18 and older will provide samples during a single visit, where they will also answer questions about their health. The collected samples will be used to study the pathogenesis of emerging respiratory viruses and to develop upper respiratory tract organoids. Individuals with recent respiratory symptoms will be excluded to ensure the health of the samples.

Who should consider this trial

Good fit: Ideal candidates for this study are healthy adults aged 18 years and older who can provide informed consent.

Not a fit: Patients with a recent history of respiratory symptoms or those who are not healthy may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could enhance our understanding of respiratory viruses and lead to improved prevention and treatment strategies.

How similar studies have performed: While this approach is focused on sample collection, similar studies have successfully established biobanks for respiratory research, indicating potential for valuable insights.

Eligibility criteria

Show full inclusion / exclusion criteria
* INCLUSION CRITERIA:

In order to be eligible to participate in this study, an individual must meet all of the following criteria:

* Aged \>=18 years.
* Able to provide informed consent.
* Willing to allow biological samples and data to be stored for future research.

EXCLUSION CRITERIA:

An individual who meets any of the following criteria will be excluded from participation in this

study:

* History of respiratory symptoms including but not limited to runny nose, coughing, congestion, and/or fever within the past 14 days.
* NIH and laboratory staff with direct involvement in the operation or maintenance of the repository are excluded from participation.
* An individual who has any condition that, in the judgment of the investigator, may put them at undue risk or make them unsuitable for participation in the study will be excluded.

Where this trial is running

Hamilton, Montana

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions HealthyNasal Epithelium
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.