Collection of extra lung samples during clinical pulmonary procedures
Official title: Universal Biospecimen Collection Protocol for Extra Material From Clinical Pulmonary Procedures
Run by M.D. Anderson Cancer Center · NCT07218939 · Data updated 2026-11-12
This project will collect extra samples from lung procedures—like bronchoalveolar lavage, pleural fluid, and blood—from adult patients at MD Anderson to build a biobank for research into pulmonary problems and treatment-related lung toxicity.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 12000 (estimated) |
| Sponsor | M.D. Anderson Cancer Center Academic / other |
| Locations | 1 site (Houston, Texas) |
| Status | Recruiting |
| Started | October 8, 2025 |
| Main results expected | December 1, 2030 |
| Study ends | December 1, 2032 |
| Registry record updated | May 19, 2026 |
| Trial ID | NCT07218939 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults (18+) seen in the MD Anderson Cardiopulmonary Center who are undergoing clinical pulmonary procedures and can provide consent are the intended participants.
✕Probably not a fit
Pregnant women, prisoners, minors, and patients not undergoing pulmonary procedures or not treated at MD Anderson would not be eligible and thus would not benefit from participation.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational protocol collects residual biospecimens (bronchoalveolar lavage, pleural fluid, blood, and other leftover tissue) that remain after routine clinical pulmonary procedures. Samples are stored in a biorepository along with basic clinical data and documentation of suspected pulmonary toxicity to support laboratory translational research. Eligible adults seen in the Cardiopulmonary Center at The University of Texas M. D. Anderson Cancer Center may have extra material saved during normally scheduled procedures. Pregnant women and prisoners are excluded and no experimental treatments are given as part of this protocol.
Why it matters
Potential benefit: If successful, the biobank could help researchers identify causes and markers of pulmonary toxicity and guide better prevention and treatment strategies.
How similar studies have gone: Similar biospecimen biobanks have enabled successful translational research into lung disease and treatment toxicity, so this approach is established in the field.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: All patients over the age of 18, who are seen in the Cardiopulmonary Center and are undergoing pulmonary procedures Exclusion Criteria: Pregnant women and prisoners
Where it's running
-
The University of Texas M. D. Anderson Cancer Center
Houston, Texas, United States Recruiting
Study contacts
- Principal investigator: Ajay Sheshadri, MD — M.D. Anderson Cancer Center
- Study coordinator: Ajay Sheshadri, MD
- Email: asheshadri@mdanderson.org
- Phone: (713) 563-1987
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.