Collection of extra lung samples during clinical pulmonary procedures
Universal Biospecimen Collection Protocol for Extra Material From Clinical Pulmonary Procedures
This project will collect extra samples from lung procedures—like bronchoalveolar lavage, pleural fluid, and blood—from adult patients at MD Anderson to build a biobank for research into pulmonary problems and treatment-related lung toxicity.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 12000 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | M.D. Anderson Cancer Center Academic / other |
| Locations | 1 site (Houston, Texas) |
| Trial ID | NCT07218939 on ClinicalTrials.gov |
What this trial studies
This observational protocol collects residual biospecimens (bronchoalveolar lavage, pleural fluid, blood, and other leftover tissue) that remain after routine clinical pulmonary procedures. Samples are stored in a biorepository along with basic clinical data and documentation of suspected pulmonary toxicity to support laboratory translational research. Eligible adults seen in the Cardiopulmonary Center at The University of Texas M. D. Anderson Cancer Center may have extra material saved during normally scheduled procedures. Pregnant women and prisoners are excluded and no experimental treatments are given as part of this protocol.
Who should consider this trial
Good fit: Adults (18+) seen in the MD Anderson Cardiopulmonary Center who are undergoing clinical pulmonary procedures and can provide consent are the intended participants.
Not a fit: Pregnant women, prisoners, minors, and patients not undergoing pulmonary procedures or not treated at MD Anderson would not be eligible and thus would not benefit from participation.
Why it matters
Potential benefit: If successful, the biobank could help researchers identify causes and markers of pulmonary toxicity and guide better prevention and treatment strategies.
How similar studies have performed: Similar biospecimen biobanks have enabled successful translational research into lung disease and treatment toxicity, so this approach is established in the field.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: All patients over the age of 18, who are seen in the Cardiopulmonary Center and are undergoing pulmonary procedures Exclusion Criteria: Pregnant women and prisoners
Where this trial is running
Houston, Texas
- The University of Texas M. D. Anderson Cancer Center — Houston, Texas, United States (Recruiting)
Study contacts
- Principal investigator: Ajay Sheshadri, MD — M.D. Anderson Cancer Center
- Study coordinator: Ajay Sheshadri, MD
- Email: asheshadri@mdanderson.org
- Phone: (713) 563-1987
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.