Clinical trial Recruiting at 1 site Observational Ages 18 and up

Collection of blood samples from adults with brain tumors

Official title: Circulating Biomarkers Repository in Adults Diagnosed With Primary and Metastatic Brain Tumors

Run by Duke University · NCT05480644 · Data updated 2026-11-12

This study is collecting blood samples from adults with brain tumors to see if certain markers in the blood can help improve treatment outcomes after radiation therapy.

More Brain Metastases, Adult trials

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment300 (estimated)
SponsorDuke University
Academic / other
Drugs / interventionsRadiation
Locations1 site (Durham, North Carolina)
StatusRecruiting
StartedDecember 1, 2022
Main results expectedDecember 2032
Study endsDecember 2032
Registry record updatedOctober 20, 2026
Trial IDNCT05480644 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are adults who have a confirmed diagnosis of primary or metastatic brain tumors.

Probably not a fit

Patients without a confirmed diagnosis of brain tumors will not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to create a repository of blood samples from adults diagnosed with primary and metastatic brain tumors at the Duke Cancer Center. The collected samples will be analyzed to investigate the relationship between circulating biomarkers and the outcomes of radiation therapy. By understanding these associations, the study seeks to enhance treatment strategies for patients with brain tumors. The observational nature of the study allows for the collection of valuable data without any specified interventions.

Why it matters

Potential benefit: If successful, this study could lead to improved treatment outcomes for patients with brain tumors by identifying biomarkers that predict responses to radiation therapy.

How similar studies have gone: Other studies have shown promise in using circulating biomarkers to predict treatment outcomes in various cancers, suggesting potential success for this approach.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Have a confirmed diagnosis of primary or metastatic brain tumor (histology or imaging as appropriate)

Exclusion Criteria:

* None

Where it's running

  • Duke Cancer Center
    Durham, North Carolina, United States
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.