Collection of blood samples from adults with brain tumors
Official title: Circulating Biomarkers Repository in Adults Diagnosed With Primary and Metastatic Brain Tumors
Run by Duke University · NCT05480644 · Data updated 2026-11-12
This study is collecting blood samples from adults with brain tumors to see if certain markers in the blood can help improve treatment outcomes after radiation therapy.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 300 (estimated) |
| Sponsor | Duke University Academic / other |
| Drugs / interventions | Radiation |
| Locations | 1 site (Durham, North Carolina) |
| Status | Recruiting |
| Started | December 1, 2022 |
| Main results expected | December 2032 |
| Study ends | December 2032 |
| Registry record updated | October 20, 2026 |
| Trial ID | NCT05480644 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are adults who have a confirmed diagnosis of primary or metastatic brain tumors.
✕Probably not a fit
Patients without a confirmed diagnosis of brain tumors will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study aims to create a repository of blood samples from adults diagnosed with primary and metastatic brain tumors at the Duke Cancer Center. The collected samples will be analyzed to investigate the relationship between circulating biomarkers and the outcomes of radiation therapy. By understanding these associations, the study seeks to enhance treatment strategies for patients with brain tumors. The observational nature of the study allows for the collection of valuable data without any specified interventions.
Why it matters
Potential benefit: If successful, this study could lead to improved treatment outcomes for patients with brain tumors by identifying biomarkers that predict responses to radiation therapy.
How similar studies have gone: Other studies have shown promise in using circulating biomarkers to predict treatment outcomes in various cancers, suggesting potential success for this approach.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Have a confirmed diagnosis of primary or metastatic brain tumor (histology or imaging as appropriate) Exclusion Criteria: * None
Where it's running
-
Duke Cancer Center
Durham, North Carolina, United States Recruiting
Study contacts
- Principal investigator: Eugene Vaios, MD MBA — Duke University Health System (DUHS)
- Study coordinator: Kaitlin Bailey, RN OCN
- Email: Kaitlin.Bailey@duke.edu
- Phone: (919) 668-3726
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.