Collection of biological samples from children with liver tumors
Constitution of a Centralized Biological Resources Collection and Associated With a Clinical Database for Childhood Liver Tumors Diagnosed in France (Retrospective Collection From 1990 and Prospective)
This study is collecting samples from children with liver tumors to help doctors better understand and treat these cancers.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 600 (estimated) |
| Ages | N/A to 18 Years |
| Sex | All |
| Sponsor | Gustave Roussy, Cancer Campus, Grand Paris Academic / other |
| Locations | 1 site (Villejuif, Val De Marne) |
| Trial ID | NCT04274868 on ClinicalTrials.gov |
What this trial studies
This observational study focuses on the centralized collection of biological samples from children and adolescents diagnosed with primary liver tumors in France. It aims to gather both retrospective and prospective data, including tissues and fluids, to support the diagnostic and therapeutic management of these patients. The study is backed by the French Society for Childhood Cancers and includes a clinical database to facilitate research and improve understanding of liver tumors in pediatric populations.
Who should consider this trial
Good fit: Ideal candidates include children and adolescents aged 18 years or younger diagnosed with a primary liver tumor after January 1, 1990, and treated in France.
Not a fit: Patients who do not have a primary liver tumor or were diagnosed before January 1, 1990, may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance the understanding and treatment of liver tumors in children, leading to better patient outcomes.
How similar studies have performed: While this approach is focused on a specific population, similar studies involving biological sample collections in pediatric oncology have shown promise in advancing treatment and understanding of various cancers.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. - For inclusion in the clinical database: * Children and adolescents (≤18 years at diagnosis) suffering from a primary liver tumor diagnosed after 01/01/1990 and treated in France * Informed consent to the computerization of data signed by the patient or by parents or legal representatives if he is a minor. 2. - For inclusion in the biological collection (CRB Paris Sud): * Additional criteria: * Availability of biological samples (tumor tissue, healthy tissue, plasma and / or serum). * Informed consent to the use of biological remains signed by the patient or by parents or legal representatives if he is a minor. 3. - For the inclusion of deceased patients: * Obtaining consent or failing this, seeking non-opposition to the computerization of data (for inclusion in the database) and the use of biological remains (for inclusion in the biological collection) of the patient or both parents or the legal guardian if he is a minor. Exclusion Criteria: * None
Where this trial is running
Villejuif, Val De Marne
- Gustave Roussy — Villejuif, Val De Marne, France (Recruiting)
Study contacts
- Study coordinator: Brenda Mallon
- Email: branda.mallon@gustaveroussy.fr
- Phone: 0142114211
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.