Collection and analysis of blood and tissue samples from healthy volunteers
Procurement and Analysis of Blood, Bone Marrow, and Buccal Mucosa Samples From Healthy Volunteers to Support Clinical and Translational Research Projects in the NHLBI
This study is looking for healthy volunteers to donate blood and tissue samples to help researchers learn more about blood cell formation and diseases like aplastic anemia.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 1000 (estimated) |
| Ages | 8 Years to 99 Years |
| Sex | All |
| Sponsor | National Institutes of Health Clinical Center (CC) NIH |
| Locations | 1 site (Bethesda, Maryland) |
| Trial ID | NCT00442195 on ClinicalTrials.gov |
What this trial studies
The Hematology Branch of the National Heart, Lung, and Blood Institute is conducting laboratory experiments that require blood and tissue samples from healthy volunteers aged 8 years and older. This protocol facilitates the collection of blood, bone marrow, skin tissue, and buccal mucosa samples for research on blood cell formation, viral blood diseases, immune system roles in marrow failure, and genetic factors related to aplastic anemia. Participants will donate samples through standard medical procedures, and these samples will be crucial for various clinical and translational research projects.
Who should consider this trial
Good fit: Ideal candidates are healthy volunteers aged 8 years and older.
Not a fit: Patients with recent abnormal blood counts or those who are pregnant may not benefit from this study.
Why it matters
Potential benefit: If successful, this research could enhance our understanding of blood diseases and improve future treatments.
How similar studies have performed: Other studies involving sample collection from healthy volunteers have shown success in advancing our understanding of various medical conditions.
Eligibility criteria
Show full inclusion / exclusion criteria
* INCLUSION CRITERIA: Self-declared healthy volunteer (for blood and buccal mucosa sample donors). Be healthy, as determined by Principal Investigator or designee based on recent (\<3 months) history, physical and laboratory results (for bone marrow and skin tissue sample donors). \<TAB\>\<TAB\>\<TAB\>\<TAB\>\<TAB\> Age 8 years and older (no upper limit) for blood and buccal mucosa sampling. OR Ages 18 years or older (no upper limit) for bone marrow or skin tissue sampling. EXCLUSION CRITERIA: Unable to comprehend the investigational nature of the protocol participation. CBC determined outside expected normal ranges for the subject (bone marrow and skin tissue donors only). Pregnancy Age less than 18 years for skin tissue sampling, bone marrow aspirate and biopsy. Off campus volunteers for skin tissue sampling bone marrow aspirate and biopsy.
Where this trial is running
Bethesda, Maryland
- National Institutes of Health Clinical Center — Bethesda, Maryland, United States (Recruiting)
Study contacts
- Principal investigator: Neal S Young, M.D. — National Heart, Lung, and Blood Institute (NHLBI)
- Study coordinator: OPR Office of Patient Recruitment
- Email: ccopr@nih.gov
- Phone: (800) 411-1222
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.