Clinical trial Recruiting at 1 site Observational Ages 18 and up

Collecting tissue samples to understand solid tumors better

Official title: Tissue Collection Framework To Improve Outcomes In Solid Tumours

Run by Queen Mary University of London · NCT03572192 · Data updated 2026-11-12

This study is collecting tissue samples from cancer patients to see how solid tumors work and why some treatments don't always work, with the hope of finding better therapies in the future.

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment3000 (estimated)
SponsorQueen Mary University of London
Academic / other
Locations1 site (London)
StatusRecruiting
StartedSeptember 2013
Main results expectedAugust 2043
Study endsAugust 2043
Registry record updatedNovember 18, 2025
Trial IDNCT03572192 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are adults over 18 years old who have been diagnosed with a solid tumor and are receiving clinical management at Barts Health NHS Trust.

Probably not a fit

Patients with co-existing medical conditions that significantly increase participation risks or those unable to provide informed consent may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to collect cancer and normal tissue specimens from patients diagnosed with solid tumors to analyze them using advanced molecular profiling technologies. By examining these samples, researchers hope to uncover the mechanisms behind cancer cell metastasis and drug resistance, which are not well understood. The study will involve approximately 320,000 patients diagnosed with cancer in the UK each year, focusing on the genetic and molecular factors that contribute to treatment outcomes. Insights gained from this research could lead to the development of improved cancer therapies and predictive tests for treatment tolerance.

Why it matters

Potential benefit: If successful, this study could lead to better cancer treatments that prevent drug resistance and improve patient survival rates.

How similar studies have gone: Other studies utilizing molecular profiling techniques have shown promise in understanding cancer mechanisms, suggesting that this approach may yield valuable insights.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. Male and female patients over the age of 18 years who have been diagnosed with a solid tumour and who are seen at the Barts Health NHS Trust for clinical management of their tumour.
2. Male or female more than 18 years of age
3. Able to participate in the study.
4. Able to give informed consent.
5. Patients enrolled into other clinical trials may be included into this study

Exclusion Criteria

1. Any co-existing medical condition that in the Investigator's judgement will substantially increase the risk associated with the patient's participation in the study
2. Psychiatric disorders or altered mental status precluding understanding of the informed consent process and/or completion of the necessary studies
3. Physical or mental health issues that preclude them from participation

Where it's running

  • St Bartholomew's Hospital
    London, United Kingdom
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.