Collecting tissue samples to understand solid tumors better
Tissue Collection Framework To Improve Outcomes In Solid Tumours
This study is collecting tissue samples from cancer patients to see how solid tumors work and why some treatments don't always work, with the hope of finding better therapies in the future.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 3000 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Queen Mary University of London Academic / other |
| Locations | 1 site (London) |
| Trial ID | NCT03572192 on ClinicalTrials.gov |
What this trial studies
This observational study aims to collect cancer and normal tissue specimens from patients diagnosed with solid tumors to analyze them using advanced molecular profiling technologies. By examining these samples, researchers hope to uncover the mechanisms behind cancer cell metastasis and drug resistance, which are not well understood. The study will involve approximately 320,000 patients diagnosed with cancer in the UK each year, focusing on the genetic and molecular factors that contribute to treatment outcomes. Insights gained from this research could lead to the development of improved cancer therapies and predictive tests for treatment tolerance.
Who should consider this trial
Good fit: Ideal candidates for this study are adults over 18 years old who have been diagnosed with a solid tumor and are receiving clinical management at Barts Health NHS Trust.
Not a fit: Patients with co-existing medical conditions that significantly increase participation risks or those unable to provide informed consent may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to better cancer treatments that prevent drug resistance and improve patient survival rates.
How similar studies have performed: Other studies utilizing molecular profiling techniques have shown promise in understanding cancer mechanisms, suggesting that this approach may yield valuable insights.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Male and female patients over the age of 18 years who have been diagnosed with a solid tumour and who are seen at the Barts Health NHS Trust for clinical management of their tumour. 2. Male or female more than 18 years of age 3. Able to participate in the study. 4. Able to give informed consent. 5. Patients enrolled into other clinical trials may be included into this study Exclusion Criteria 1. Any co-existing medical condition that in the Investigator's judgement will substantially increase the risk associated with the patient's participation in the study 2. Psychiatric disorders or altered mental status precluding understanding of the informed consent process and/or completion of the necessary studies 3. Physical or mental health issues that preclude them from participation
Where this trial is running
London
- St Bartholomew's Hospital — London, United Kingdom (Recruiting)
Study contacts
- Study coordinator: Thomas Powles
- Email: bci-orchidtrials@qmul.ac.uk
- Phone: 0207 882 8762
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.