Collecting tissue samples from cancer patients and healthy participants
Tissue Procurement and Outcome Collection for Radiotherapy Treated Patients and Healthy Participants
University of Texas Southwestern Medical Center · NCT00992303
This study is collecting tissue samples from cancer patients receiving radiation therapy and healthy individuals to see how genetic differences affect treatment outcomes and to build a resource for future research.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 10000 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | University of Texas Southwestern Medical Center (other) |
| Drugs / interventions | chemotherapy, radiation |
| Locations | 1 site (Dallas, Texas) |
| Trial ID | NCT00992303 on ClinicalTrials.gov |
What this trial studies
This research involves collecting and preserving tissue samples from patients with cancer who are undergoing radiation therapy, as well as samples from healthy participants for comparison. The primary objective is to create a tissue resource and database at the University of Texas Southwestern Medical Center to study genetic variations and their impact on clinical outcomes. Secondary objectives include documenting disease outcomes and treatment-related toxicity, as well as establishing a registry for future research. Participants will be followed up regularly to gather comprehensive data on their health and treatment responses.
Who should consider this trial
Good fit: Ideal candidates include adults over 18 with a pathologically-proven diagnosis of malignancy who are planning to undergo radiation therapy.
Not a fit: Patients who are unable to provide follow-up or future contact will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance our understanding of cancer biology and improve treatment outcomes for patients.
How similar studies have performed: Other studies have successfully utilized similar approaches to collect and analyze tissue samples for cancer research, indicating a promising avenue for future investigations.
Eligibility criteria
Show full inclusion / exclusion criteria
DISEASE CHARACTERISTICS: * Pathologically-proven diagnosis of malignancy * Planning treatment with radiation therapy PATIENT CHARACTERISTICS: * Able to perform follow-up visits * Is a patient of the University of Texas Southwestern Medical Center physicians PRIOR CONCURRENT THERAPY: * See Disease Characteristics * Participation in other clinical trials is allowed * Other prior or concurrent therapy for cancer, such as surgery and/or chemotherapy, is allowed. Criteria for eligibility: * Able to provide written informed consent * Age greater than 18 years old * Males and Females are eligible * Any ethnicity is eligible Criteria for ineligibility: -Patients not available for follow-up/future contact
Where this trial is running
Dallas, Texas
- UT Southwestern Medical Center — Dallas, Texas, United States (RECRUITING)
Study contacts
- Principal investigator: Robert Timmerman, MD — University of Texas Southwestern Medical Center - Dallas
- Study coordinator: Suprabha Pulipparacharuvil
- Email: suprabha.pulipparacharuvil@utsouthwestern.edu
- Phone: 214-645-8525
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Unspecified Adult Solid Tumor, Protocol Specific, unspecified adult solid tumor, protocol specific