Collecting tissue samples from cancer patients and healthy participants
Official title: Tissue Procurement and Outcome Collection for Radiotherapy Treated Patients and Healthy Participants
Run by University of Texas Southwestern Medical Center · NCT00992303 · Data updated 2026-11-12
This study is collecting tissue samples from cancer patients receiving radiation therapy and healthy individuals to see how genetic differences affect treatment outcomes and to build a resource for future research.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 10000 (estimated) |
| Sponsor | University of Texas Southwestern Medical Center Academic / other |
| Drugs / interventions | chemotherapy, radiation |
| Locations | 1 site (Dallas, Texas) |
| Status | Recruiting |
| Started | September 2009 |
| Main results expected | December 2029 |
| Study ends | December 2029 |
| Registry record updated | July 17, 2026 |
| Trial ID | NCT00992303 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include adults over 18 with a pathologically-proven diagnosis of malignancy who are planning to undergo radiation therapy.
✕Probably not a fit
Patients who are unable to provide follow-up or future contact will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This research involves collecting and preserving tissue samples from patients with cancer who are undergoing radiation therapy, as well as samples from healthy participants for comparison. The primary objective is to create a tissue resource and database at the University of Texas Southwestern Medical Center to study genetic variations and their impact on clinical outcomes. Secondary objectives include documenting disease outcomes and treatment-related toxicity, as well as establishing a registry for future research. Participants will be followed up regularly to gather comprehensive data on their health and treatment responses.
Why it matters
Potential benefit: If successful, this study could enhance our understanding of cancer biology and improve treatment outcomes for patients.
How similar studies have gone: Other studies have successfully utilized similar approaches to collect and analyze tissue samples for cancer research, indicating a promising avenue for future investigations.
Who can join: the full rules
Show full inclusion / exclusion criteria
DISEASE CHARACTERISTICS: * Pathologically-proven diagnosis of malignancy * Planning treatment with radiation therapy PATIENT CHARACTERISTICS: * Able to perform follow-up visits * Is a patient of the University of Texas Southwestern Medical Center physicians PRIOR CONCURRENT THERAPY: * See Disease Characteristics * Participation in other clinical trials is allowed * Other prior or concurrent therapy for cancer, such as surgery and/or chemotherapy, is allowed. Criteria for eligibility: * Able to provide written informed consent * Age greater than 18 years old * Males and Females are eligible * Any ethnicity is eligible Criteria for ineligibility: -Patients not available for follow-up/future contact
Where it's running
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UT Southwestern Medical Center
Dallas, Texas, United States Recruiting
Study contacts
- Principal investigator: Robert Timmerman, MD — University of Texas Southwestern Medical Center - Dallas
- Study coordinator: Suprabha Pulipparacharuvil
- Email: suprabha.pulipparacharuvil@utsouthwestern.edu
- Phone: 214-645-8525
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.