Collecting teeth and tissue from patients needing wisdom tooth removal

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to collect data and surgical waste tissue from individuals aged 16 to 50 who require third molar extraction at the NIH NIDCR Dental clinic. Participants will undergo a screening visit, a surgery visit for tooth extraction, and a follow-up visit for post-operative evaluation. The collected specimens will be used for research to enhance understanding of oral health and improve dental surgical skills. The study seeks to enroll a convenience sample of up to 10,000 subjects to gather generalizable knowledge about tooth diseases.

Why it matters

Who can join: the full rules

* INCLUSION CRITERIA:
* Ages greater than or equal to 16-50 years
* Clinical evidence of need for third molar extraction as determined by medical, dental, and radiographic evaluation by a NIDCR oral surgeon
* Willing to allow for the collection of extracted waste tissue (e.g., teeth, alveolar bone, excessive gingival tissue) to be used for research
* In good general health as defined by the American Society of Anesthesiologists (ASA) status I or II
* Able to understand and sign an informed consent

EXCLUSION CRITERIA:

* Pregnant or nursing women
* Unable to have third molar extraction as determined by NIDCR surgeon/dentist, due to medical conditions (beyond ASA I or II), complexity of the surgery, or history that precludes safe outpatient conscious sedation. These clinical decisions will be based on the risks and benefits related to the surgery.

Where it's running

• National Institutes of Health Clinical Center
  Bethesda, Maryland, United States Recruiting

Study contacts

• Principal investigator: Janice S Lee, DDS, MD — National Institute of Dental and Craniofacial Research (NIDCR)
• Study coordinator: Sharon M Mitchell
• Email: sharon.mitchell@nih.gov
• Phone: (301) 496-4372

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.