Collecting samples and data from patients with amyloid diseases
Official title: Data, Tissue, Blood, and Urine Repository for Amyloid Diseases
Run by Boston Medical Center · NCT00898235 · Data updated 2026-11-12
This study is collecting blood, urine, and tissue samples from people with amyloid diseases like multiple myeloma to see how these samples relate to their health and help improve future research.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 10000 (estimated) |
| Sponsor | Boston Medical Center Academic / other |
| Locations | 1 site (Boston, Massachusetts) |
| Status | Recruiting |
| Started | January 2000 |
| Main results expected | December 2040 |
| Study ends | December 2040 |
| Registry record updated | December 1, 2025 |
| Trial ID | NCT00898235 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are individuals diagnosed or suspected of having amyloidosis who are referred to the Amyloid Treatment and Research Center at Boston University Medical Center.
✕Probably not a fit
Patients who do not have a diagnosis or suspicion of amyloidosis will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This research focuses on gathering and storing blood, urine, tissue, and clinical data from patients diagnosed with amyloid diseases, particularly multiple myeloma. The collected samples will be used to establish a comprehensive database that correlates clinical outcomes with biological markers. Techniques such as polymerase chain reaction and various forms of spectroscopy will be employed to analyze the samples for specific amyloid protein characteristics and modifications. The study aims to enhance understanding of amyloid diseases and support future research efforts.
Why it matters
Potential benefit: If successful, this study could lead to improved diagnostic and therapeutic strategies for patients with amyloid diseases.
How similar studies have gone: Other studies focusing on the collection and analysis of biospecimens in amyloid diseases have shown promise in advancing understanding and treatment options.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: DISEASE CHARACTERISTICS: * Diagnosis or suspicion of amyloidosis PATIENT CHARACTERISTICS: * Referred to the Amyloid Treatment and Research Center at Boston University Medical Center PRIOR CONCURRENT THERAPY: * Not specified Exclusion Criteria: None
Where it's running
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Boston University Cancer Research Center
Boston, Massachusetts, United States Recruiting
Study contacts
- Principal investigator: Vaishali Sanchorawala, MD — Boston Medical Center
- Study coordinator: Vaishali Sanchorawala, MD
- Email: vaishali.sanchorawala@bmc.org
- Phone: 617-638-8261
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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6MW5311 in adults with relapsed or refractory blood cancers
This study tests increasing doses of 6MW5311 in adults with multiple myeloma, AML, or CMML to see if it is safe and tolerable and to find a suitable dose for later studies.
-
Tailored exercise program to improve quality of life for adults with hematologic cancers
This pilot trial tests a personalized 16-week exercise program to see if it’s feasible and helpful for adults with acute myeloid leukemia, lymphoma, or multiple myeloma after first-line treatment.
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Aspirin vs. rivaroxaban for blood clot prevention in newly diagnosed multiple myeloma
In newly diagnosed multiple myeloma patients on IMiD-based therapy, this study tests whether aspirin or rivaroxaban is better at preventing blood clots.
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Exercise phenotyping before chemotherapy in newly diagnosed multiple myeloma
This observational study tests whether some newly diagnosed multiple myeloma patients with normal resting heart function already show limited exercise capacity, and whether that limitation relates to subtle heart tissue changes and future heart-related outcomes.
-
SMS text check-ins to track symptoms for people with plasma cell disorders
This study tests whether daily SMS symptom prompts are feasible and acceptable for adults starting treatment for multiple myeloma or AL amyloidosis.
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Cevostamab with Pomalidomide and Dexamethasone after BCMA-directed CAR T therapy in multiple myeloma
This study tests if Cevostamab combined with pomalidomide and dexamethasone can help people with multiple myeloma who have already had CAR T therapy and several prior treatments.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.