Collecting data to improve treatment for young colorectal cancer patients

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to gather high-quality clinical data and patient biomaterials from individuals diagnosed with early-onset colorectal cancer (EOCRC) to analyze treatment outcomes and survival rates. It will complement existing studies focused on adolescents and young adults with cancer, specifically examining risk factors and genetic testing. The collected data will facilitate a deeper understanding of the epidemiology and pathophysiology of EOCRC compared to average-onset colorectal cancer and healthy controls, ultimately aiding in the development of prevention and early detection strategies.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients with locoregional or metastatic colorectal cancer (CRC)
* Histologically proven CRC
* Age 18 - 49 years at time of first CRC diagnosis
* Able to understand the informed consent form
* Provide written informed consent.

Exclusion Criteria:

* Mentally incompetent patients based on the opinion of treating physician
* Inability to understand the Dutch language

Where it's running

• Netherlands Cancer Institute
  Amsterdam, North Holland, Netherlands Recruiting

Study contacts

• Principal investigator: Karen Bolhuis, MD, PhD — The Netherlands Cancer Institute
• Study coordinator: Ruud Weijer, PhD
• Email: r.weijer@nki.nl
• Phone: +31205129111

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Gut microbiome clues for colorectal cancer risk, progression, and outcomes

  This study will try to find whether patterns in stool microbes can mark disease stage, prognosis, or treatment response in people aged 40–74 newly diagnosed with colorectal cancer.

  Recruiting at 2 sites Gulbenkian Institute for Molecular Medicine · Lisbon, Lisbon District and 1 other locations · NCT06734156

• Investigating risk factors for early-onset colorectal cancer

  This study is trying to find out what lifestyle and dietary factors might increase the risk of developing colorectal cancer in people under 50.

  Recruiting at 8 sites San Raffaele University · Denver, Colorado and 7 other locations · NCT05732623

• Early-Onset GI Cancer: From Tumor Features to Patient Habits

  This study tests how tumor biology and a patient’s lifestyle choices come together in people diagnosed with early-onset gastrointestinal cancer.

  Recruiting at 5 sites Gruppo Oncologico Italiano di Ricerca Clinica · Bologna, BO and 10 other locations · NCT07479472

• Simethicone-containing bowel prep for colon cancer screening

  This study tests a simethicone-containing evacuating solution to see if it helps people get a clean colonoscopy for colorectal cancer screening.

  Recruiting Phase 4 Fundacion Clinic per a la Recerca Biomédica · Barcelona, Barcelona · NCT07696793

• Outcomes after non-curative endoscopic removal of early colorectal cancer

  This project will compare additional surgery versus surveillance to see if one approach leads to fewer recurrences and better survival for adults with early colorectal cancer after non-curative endoscopic resection.

  Recruiting at 3 sites Nanfang Hospital, Southern Medical University · Guangzhou, Guangdong and 2 other locations · NCT07542171

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.