Clinical trial Recruiting at 1 site Observational

Collecting data on patients with bone metastases treated for fractures

Official title: Prospective Bone Metastases Database

Run by Istituto Ortopedico Rizzoli · NCT03416959 · Data updated 2026-11-12

This study is trying to see how different surgical treatments for bone fractures in cancer patients affect their recovery and survival.

Quick facts

Study typeObservational
SexAll
Enrollment120 (estimated)
SponsorIstituto Ortopedico Rizzoli
Academic / other
Locations1 site (Bologna, Bologna)
StatusRecruiting
StartedJanuary 1, 2018
Main results expectedDecember 31, 2027
Study endsDecember 31, 2027
Registry record updatedAugust 1, 2025
Trial IDNCT03416959 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are patients with long bone metastases who are undergoing surgical treatment with intramedullary nails or endoprosthetic reconstruction.

Probably not a fit

Patients with bone metastases of the spine will not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to gather prospective data on the natural history of bone metastases and skeletal-related events in patients who have undergone surgical treatment for impending or pathologic fractures of long bones. It will evaluate clinical and biological factors, focusing on complication rates, functional outcomes, and survival differences based on various patient characteristics. The study will compare outcomes between those treated with intramedullary fixation and endoprosthetic reconstruction, providing insights into the effectiveness of these surgical approaches.

Why it matters

Potential benefit: If successful, this study could improve treatment strategies and outcomes for patients with bone metastases.

How similar studies have gone: Other studies have explored similar surgical interventions for bone metastases, but this specific observational approach is less common.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients with long bone metastases treated surgically with intramedullary nail or endoprosthetic reconstruction

Exclusion Criteria:

* Patients with bone metastases of the spine

Where it's running

  • Istituto Ortopedico Rizzoli
    Bologna, Bologna, Italy
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.