Collecting data on patients with bone metastases treated for fractures

Prospective Bone Metastases Database

Observational Istituto Ortopedico Rizzoli · NCT03416959

This study is trying to see how different surgical treatments for bone fractures in cancer patients affect their recovery and survival.

Quick facts

Study typeObservational
Enrollment120 (estimated)
SexAll
SponsorIstituto Ortopedico Rizzoli Academic / other
Locations1 site (Bologna, Bologna)
Trial IDNCT03416959 on ClinicalTrials.gov

What this trial studies

This study aims to gather prospective data on the natural history of bone metastases and skeletal-related events in patients who have undergone surgical treatment for impending or pathologic fractures of long bones. It will evaluate clinical and biological factors, focusing on complication rates, functional outcomes, and survival differences based on various patient characteristics. The study will compare outcomes between those treated with intramedullary fixation and endoprosthetic reconstruction, providing insights into the effectiveness of these surgical approaches.

Who should consider this trial

Good fit: Ideal candidates are patients with long bone metastases who are undergoing surgical treatment with intramedullary nails or endoprosthetic reconstruction.

Not a fit: Patients with bone metastases of the spine will not benefit from this study.

Why it matters

Potential benefit: If successful, this study could improve treatment strategies and outcomes for patients with bone metastases.

How similar studies have performed: Other studies have explored similar surgical interventions for bone metastases, but this specific observational approach is less common.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients with long bone metastases treated surgically with intramedullary nail or endoprosthetic reconstruction

Exclusion Criteria:

* Patients with bone metastases of the spine

Where this trial is running

Bologna, Bologna

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Neoplasm Metastasis
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.