Clinical trial Recruiting at 1 site Observational Ages 18 and up

Collecting data on cellular immunotherapy for lymphoma patients

Official title: Cellular Immunotherapy for Relapsed or Refractory Lymphoma Data Collection

Run by Ruijin Hospital · NCT06541327 · Data updated 2026-11-12

This study is gathering information from adults with relapsed or hard-to-treat non-Hodgkin's lymphoma who are getting cellular immunotherapy to see how well it works and how safe it is.

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment1000 (estimated)
SponsorRuijin Hospital
Academic / other
Drugs / interventionsCAR-T, chimeric antigen receptor, immunotherapy
Locations1 site (Shanghai)
StatusRecruiting
StartedMay 15, 2024
Main results expectedDecember 31, 2040
Study endsDecember 31, 2040
Registry record updatedAugust 19, 2024
Trial IDNCT06541327 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are adult patients with a confirmed diagnosis of relapsed or refractory non-Hodgkin's lymphoma who have received or are receiving cellular immunotherapy.

Probably not a fit

Patients who do not have a diagnosis of relapsed or refractory non-Hodgkin's lymphoma or who have not received cellular immunotherapy may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to gather clinical data from adult patients with relapsed or refractory non-Hodgkin's lymphoma who are receiving cellular immunotherapy. The study will collect efficacy and safety data over a period from January 2017 to December 2040, focusing on various types of cellular immunotherapy treatments. Investigators will analyze the data to determine optimal diagnostic and treatment plans based on clinical practice, without any intervention from the study itself. Data will be collected at multiple time points, including before treatment, on the day of infusion, and during follow-up visits within 24 months post-infusion.

Why it matters

Potential benefit: If successful, this study could enhance understanding of cellular immunotherapy's effectiveness and safety for lymphoma patients, potentially leading to improved treatment strategies.

How similar studies have gone: Other studies on cellular immunotherapy have shown promising results, indicating that this approach is gaining traction in the treatment of lymphoma.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Adult patients with a confirmed diagnosis of r/r B-NHL (including r/r DLBCL, r/r FL, r/r MCL, HGBL-NOS, FL3b, r/r MZL, transformed lymphomas such as MCL) and r/r T-cell lymphoma, who have received informed consent waivers;
* Patients who have received or are receiving cellular immunotherapy, with cellular immunotherapy products including the following categories: cytokine-induced killer cell therapy (CIK), tumor-infiltrating lymphocytes (TIL), cytokine-induced killer cell-dendritic cell mixed therapy (DC-CIK), chimeric antigen receptor T cells, NK cells or macrophage therapy (CAR-T, CAR-NK, CAR-M), T-cell receptor chimeric T cell therapy (TCR-T), dendritic cell therapy.

Exclusion Criteria:

* NA

Where it's running

  • Department of Hematology, Shanghai Institute of Hematology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine
    Shanghai, China
    Recruiting

Study contacts

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.