Collecting data and samples for research on histiocytic disorders
Clinical and Molecular Characteristics of Histiocytic Disorders
Mayo Clinic · NCT06331377
This study is collecting medical histories and samples from people with histiocytic disorders to learn more about their genetics and find better treatment options.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 500 (estimated) |
| Ages | 1 Year and up |
| Sex | All |
| Sponsor | Mayo Clinic (other) |
| Locations | 1 site (Rochester, Minnesota) |
| Trial ID | NCT06331377 on ClinicalTrials.gov |
What this trial studies
This observational study aims to gather medical and personal histories, along with blood and tissue samples from patients diagnosed with histiocytic disorders. The primary objectives include defining the molecular signature and genomic landscape of these disorders, correlating genomic findings with transcriptional abnormalities, and identifying potential prognostic alterations and therapeutic targets. Patients will complete questionnaires and have their medical records reviewed as part of the data collection process.
Who should consider this trial
Good fit: Ideal candidates for this study are patients aged 1 year and older who have been diagnosed with histiocytic disorders.
Not a fit: Patients younger than 1 year old will not be eligible to participate in this study.
Why it matters
Potential benefit: If successful, this study could lead to improved understanding and treatment options for patients with histiocytic disorders.
How similar studies have performed: Other studies focusing on the genomic and molecular characteristics of similar disorders have shown promise, indicating potential for success in this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * \* All patients diagnosed with histiocytic disorders and age ≥1 year Exclusion Criteria: * \* \< 1 years age
Where this trial is running
Rochester, Minnesota
- Mayo Clinic in Rochester — Rochester, Minnesota, United States (RECRUITING)
Study contacts
- Principal investigator: Ronald S. Go, M.D. — Mayo Clinic in Rochester
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Histiocytic Disorder