Collecting COVID-19 virus secretions and serum for developing treatments

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to collect SARS-CoV-2 secretions and serum from patients to understand the natural history of COVID-19 infections and characterize post-COVID morbidity. It focuses on analyzing immune responses, virus genome sequencing, cytokine responses, and virus shedding in both acutely infected and convalescent patients. The study will establish a data registry to track viral sequences and clinical courses, helping to identify predictors of severe outcomes and optimize treatment strategies for high-risk populations.

Why it matters

Who can join: the full rules

Population 1:

Inclusion Criteria:

1. Positive diagnostic test for COVID-19, influenza A or B virus, non COVID-19 coronavirus, parainfluenza virus, rhinovirus, adenovirus, or metapneumovirus
2. Patient or legally authorized representative has provided verbal consent / verbal HIPAA (or parental permission form and assent form, as appropriate)

Exclusion Criteria:

* None

Population 2:

Inclusion Criteria:

1. Positive diagnostic test for COVID-19 \>14 days prior, OR potential to have been exposed to (and mounted antibodies against) COVID-19, OR positive diagnostic test for influenza A or B virus, non COVID-19 coronavirus, parainfluenza virus, rhinovirus, adenovirus, or metapneumovirus
2. Patient or legally authorized representative has signed informed consent (or parental permission form and assent form, as appropriate)

Exclusion Criteria:

Patients with the following criteria:

* Aged under 6 months old
* Anemia (Hgb \<7)
* Platelet \<80

Where it's running

• Tulane University Medical Center
  New Orleans, Louisiana, United States Recruiting
• University Medical Center New Orleans
  New Orleans, Louisiana, United States Recruiting

Study contacts

• Principal investigator: Dahlene Fusco, MD, PhD — Tulane University School of Medicine
• Study coordinator: Dahlene Fusco, MD, PhD
• Email: dfusco@tulane.edu
• Phone: 504-988-7316

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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• Registry to evaluate pregnancy outcomes in women treated for COVID-19

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• Using donor-derived T cells to treat mild to moderate COVID-19

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  Recruiting Phase 1/2 New York Medical College · Valhalla, New York and 3 other locations · NCT04896606

• Observational study on the biology of COVID-19 in Saarland

  This study looks at how COVID-19 affects people in different ways, including those with long-term symptoms, to learn more about the disease and its progression.

  Recruiting Universität des Saarlandes · Homburg, Saarland · NCT04837755

• Imaging immune activation in COVID-19 patients

  This study is testing a special imaging technique to see how the immune system is working in people who have recently recovered from COVID-19.

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• AGILE: an early-phase platform testing treatments for COVID-19

  This project tests several experimental antiviral and immune therapies to see if they are safe and work for adults with confirmed COVID-19.

  Recruiting at 4 sites Phase 1/2 University of Liverpool · Cape Town and 6 other locations · NCT04746183

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.