Collecting blood samples from HIV-positive and HIV-negative individuals
Collection and Preservation of Blood and Serum Specimens From HIV Positive or HIV Negative Patients for Multiple Collaborative Studies
University of California, San Francisco · NCT01336855
This study is collecting blood samples from people with and without HIV to help researchers learn more about the virus and improve treatments.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 2000 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | University of California, San Francisco (other) |
| Locations | 1 site (San Francisco, California) |
| Trial ID | NCT01336855 on ClinicalTrials.gov |
What this trial studies
This observational study aims to collect blood samples from both HIV-positive individuals and HIV-negative controls to support various collaborative research projects focused on HIV. The collected specimens will be utilized by basic scientists to enhance the understanding of HIV's etiology, immunology, and treatment. Researchers will analyze these samples for virus characteristics, drug resistance, immune function, and genetic factors related to HIV disease progression. The study emphasizes the importance of these samples in advancing HIV research and improving patient outcomes.
Who should consider this trial
Good fit: Ideal candidates include HIV-positive individuals who are either naive to antiretroviral therapy or stable on treatment for at least six months, as well as HIV-negative individuals with similar characteristics.
Not a fit: Patients currently undergoing active treatment for cancer or those with severe anemia or recent immunosuppressive therapy may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could significantly enhance the understanding of HIV and lead to improved treatment strategies.
How similar studies have performed: Other studies involving the collection of biological samples for HIV research have shown success in advancing our understanding of the disease.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * HIV-1 antibody negative with similar characteristics to HIV-1 positive cohort * HIV-positive subjects naive to antiretroviral therapy * HIV-positive subjects stable on or off antiretroviral therapy for a minimum of 6 months * Good venous access * Able to provide informed consent Exclusion Criteria: * Hemoglobin \< 9g/dl * Hematocrit \< 27% * Active treatment for cancer * Hospitalization or IV antibiotic use within the last 4 months * Immunosuppressive therapy within the last 4 months
Where this trial is running
San Francisco, California
- San Francisco General Hospital — San Francisco, California, United States (RECRUITING)
Study contacts
- Principal investigator: Steven Deeks, M.D. — University of Californa, San Francisco
- Study coordinator: Rebecca Hoh, M.S., R.D.
- Email: Rebecca.Hoh@ucsf.edu
- Phone: 415-476-4082
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: HIV, Observational, Pathogenesis, Immunology, Virology, Control, Healthy control, Men who have sex with men