Collecting blood plasma and white blood cells for research
Procedures to Obtain Plasma, Lymphocytes, or Other Specimens for Research Studies
This study is collecting blood plasma and white blood cells from healthy volunteers and patients to help researchers learn more about diseases like HIV.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 3000 (estimated) |
| Ages | 18 Years to 100 Years |
| Sex | All |
| Sponsor | National Institutes of Health Clinical Center (CC) NIH |
| Locations | 1 site (Bethesda, Maryland) |
| Trial ID | NCT00114647 on ClinicalTrials.gov |
What this trial studies
This study involves the collection of blood plasma and white blood cells from participants using apheresis, a procedure that allows for the safe extraction of larger quantities of specific blood components. Participants, including healthy volunteers and those enrolled in NIH clinical research protocols, will undergo apheresis to provide samples for laboratory studies. The collected components may be used in various research projects aimed at understanding conditions like HIV and other diseases. The study is designed to facilitate the collection of these samples to support ongoing and future research efforts.
Who should consider this trial
Good fit: Ideal candidates include healthy volunteers and individuals aged 18 and older who are enrolled in NIH clinical research protocols.
Not a fit: Patients who are pregnant, breastfeeding, or have certain medical conditions may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance our understanding of HIV and other conditions, potentially leading to improved treatments.
How similar studies have performed: Other studies utilizing apheresis for sample collection have shown success in facilitating research, making this approach well-established.
Eligibility criteria
Show full inclusion / exclusion criteria
* INCLUSION CRITERIA: 18 years of age or older Adequate venous access Blood pressure less than or equal to 180/100; pulse rate 50-100, unless a lower pulse rate is considered normal for the volunteer (e.g. a conditioned athlete) Adequate blood counts if undergoing apheresis (HIV positive volunteers and volunteers with vasculitis or other inflammatory diseases: hemoglobin greater than or equal to 9.0 g/dL, HCT greater than or equal to 28%, platelets greater than or equal to 50,000; HIV negative volunteers: hemoglobin greater than or equal to 12.5 g/dL, HCT greater than or equal to 38%, platelets greater than or equal to 150,000) Willing and able to provide written informed consent, comply with study requirements and procedures, and comply with clinic policies (including stored samples, hepatitis screening, and genetic testing including HLA testing) EXCLUSION CRITERIA: Pregnant and/or breast-feeding women Currently abusing alcohol or other drugs Any medical condition for which the PI feels apheresis or other sample collection procedures might be contraindicated
Where this trial is running
Bethesda, Maryland
- National Institutes of Health Clinical Center — Bethesda, Maryland, United States (Recruiting)
Study contacts
- Principal investigator: Susan L Moir, Ph.D. — National Institute of Allergy and Infectious Diseases (NIAID)
- Study coordinator: Holly A Baus, R.N.
- Email: holly.baus@nih.gov
- Phone: (301) 761-6800
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.