Collecting and banking human tissue samples at St. Jude Children's Research Hospital
Official title: TBANK: Protocol for Collecting, Banking and Distributing Human Tissue Samples: St. Jude Children's Research Hospital Tissue Resources Core Facility
Run by St. Jude Children's Research Hospital · NCT01354002 · Data updated 2026-11-12
This study is collecting and storing tissue and fluid samples from children with diseases and their family members at St. Jude to help with future research on treatments and outcomes.
Quick facts
| Study type | Observational |
|---|---|
| Sex | All |
| Enrollment | 100000 (estimated) |
| Sponsor | St. Jude Children's Research Hospital Academic / other |
| Locations | 14 sites (Huntsville, Alabama and 13 other locations) |
| Status | Recruiting |
| Started | September 1, 2009 |
| Main results expected | December 2050 |
| Study ends | December 2050 |
| Registry record updated | November 9, 2026 |
| Trial ID | NCT01354002 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include patients and their relatives treated at St. Jude Children's Research Hospital and its affiliates who consent to participate.
✕Probably not a fit
Patients from institutions without IRB approval for tissue banking who do not provide consent will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This protocol aims to collect and store both diseased and normal tissue and body fluid samples from patients at St. Jude Children's Research Hospital and its affiliated sites. It also includes samples from relatives of patients and aims to gather corresponding clinical and laboratory data related to disease characterization, treatment, and outcomes. The samples will be banked under approved protocols and will only be released for specific research purposes. This initiative serves as a vital resource for future research involving human biological samples.
Why it matters
Potential benefit: If successful, this initiative could enhance research capabilities and lead to better understanding and treatment of various diseases in children.
How similar studies have gone: Other studies involving tissue banking have shown success in advancing research and improving patient outcomes, making this approach well-established.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients (and their relatives) and control populations treated or studied at SJCRH and SJCRH affiliates and collaborating sites that have IRB approval for TBANK with malignant and non-malignant conditions. * Patients from institutions that do not have Institutional Review Board (IRB) approval for TBANK, and at which a banking mechanism may not be established, who provide samples for research at St. Jude and from whom consent for TBANK is obtained by the TBANK principal investigator (PI). * Samples from employees of St. Jude Children's Research Hospital (SJCRH) collected for public health surveillance studies (e.g. SJTRC-NCT04362995) provided the employees have consented to participate in the specific IRB-approved studies. Exclusion Criteria: * Patients from institutions that do not have IRB approval for TBANK, and who have not provided consent for TBANK, or patients not enrolled on SJCRH protocols that incorporate consent for tumor banking.
Where it's running
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St. Jude Clinic at Huntsville Hospital for Women & Children
Huntsville, Alabama, United States Recruiting -
Lucile Packard Children's Hospital Stanford University
Palo Alto, California, United States Recruiting -
Rady Children's Hospital and Health Center
San Diego, California, United States Recruiting -
Children's Hospital of Illinois at OSF-Saint Francis Medical Center
Peoria, Illinois, United States Recruiting -
Our Lady of the Lake Regional Medical Center
Baton Rouge, Louisiana, United States Recruiting -
Louisiana State University Health Sciences Center
Shreveport, Louisiana, United States Recruiting
Show 8 more locations
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Mercy Children's Hospital - Springfield
Springfield, Missouri, United States Recruiting -
St. Jude Affiliate Clinic at Novant Health Hemby Children's Hospital
Charlotte, North Carolina, United States Recruiting -
St. Jude Affiliate Clinic at Saint Francis Children's Hospital
Tulsa, Oklahoma, United States Recruiting -
Johnson City Medical Center
Johnson City, Tennessee, United States Recruiting -
LeBonheur Children's Hospital
Memphis, Tennessee, United States Recruiting -
St. Jude Children's Research Hospital
Memphis, Tennessee, United States Recruiting -
Cook Children's Medical Center
Fort Worth, Texas, United States Recruiting -
Children's Hospital of Michigan
Detroit, Michigan, United States Suspended
Study contacts
- Principal investigator: Charles Mullighan, MBBS, MD — St. Jude Children's Research Hospital
- Study coordinator: Charles Mullighan, MBBS, MD
- Email: charles.mullighan@stjude.org
- Phone: 901-595-3387
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.