Collecting and banking human tissue samples at St. Jude Children's Research Hospital
TBANK: Protocol for Collecting, Banking and Distributing Human Tissue Samples: St. Jude Children's Research Hospital Tissue Resources Core Facility
St. Jude Children's Research Hospital · NCT01354002
This study is collecting and storing tissue and fluid samples from children with diseases and their family members at St. Jude to help with future research on treatments and outcomes.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 100000 (estimated) |
| Sex | All |
| Sponsor | St. Jude Children's Research Hospital (other) |
| Locations | 14 sites (Huntsville, Alabama and 13 other locations) |
| Trial ID | NCT01354002 on ClinicalTrials.gov |
What this trial studies
This protocol aims to collect and store both diseased and normal tissue and body fluid samples from patients at St. Jude Children's Research Hospital and its affiliated sites. It also includes samples from relatives of patients and aims to gather corresponding clinical and laboratory data related to disease characterization, treatment, and outcomes. The samples will be banked under approved protocols and will only be released for specific research purposes. This initiative serves as a vital resource for future research involving human biological samples.
Who should consider this trial
Good fit: Ideal candidates include patients and their relatives treated at St. Jude Children's Research Hospital and its affiliates who consent to participate.
Not a fit: Patients from institutions without IRB approval for tissue banking who do not provide consent will not benefit from this study.
Why it matters
Potential benefit: If successful, this initiative could enhance research capabilities and lead to better understanding and treatment of various diseases in children.
How similar studies have performed: Other studies involving tissue banking have shown success in advancing research and improving patient outcomes, making this approach well-established.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients (and their relatives) and control populations treated or studied at SJCRH and SJCRH affiliates and collaborating sites that have IRB approval for TBANK with malignant and non-malignant conditions. * Patients from institutions that do not have Institutional Review Board (IRB) approval for TBANK, and at which a banking mechanism may not be established, who provide samples for research at St. Jude and from whom consent for TBANK is obtained by the TBANK principal investigator (PI). * Samples from employees of St. Jude Children's Research Hospital (SJCRH) collected for public health surveillance studies (e.g. SJTRC-NCT04362995) provided the employees have consented to participate in the specific IRB-approved studies. Exclusion Criteria: * Patients from institutions that do not have IRB approval for TBANK, and who have not provided consent for TBANK, or patients not enrolled on SJCRH protocols that incorporate consent for tumor banking.
Where this trial is running
Huntsville, Alabama and 13 other locations
- St. Jude Clinic at Huntsville Hospital for Women & Children — Huntsville, Alabama, United States (RECRUITING)
- Lucile Packard Children's Hospital Stanford University — Palo Alto, California, United States (RECRUITING)
- Rady Children's Hospital and Health Center — San Diego, California, United States (RECRUITING)
- Children's Hospital of Illinois at OSF-Saint Francis Medical Center — Peoria, Illinois, United States (RECRUITING)
- Our Lady of the Lake Regional Medical Center — Baton Rouge, Louisiana, United States (RECRUITING)
- Louisiana State University Health Sciences Center — Shreveport, Louisiana, United States (RECRUITING)
- Children's Hospital of Michigan — Detroit, Michigan, United States (SUSPENDED)
- Mercy Children's Hospital - Springfield — Springfield, Missouri, United States (RECRUITING)
- St. Jude Affiliate Clinic at Novant Health Hemby Children's Hospital — Charlotte, North Carolina, United States (RECRUITING)
- St. Jude Affiliate Clinic at Saint Francis Children's Hospital — Tulsa, Oklahoma, United States (RECRUITING)
- Johnson City Medical Center — Johnson City, Tennessee, United States (RECRUITING)
- LeBonheur Children's Hospital — Memphis, Tennessee, United States (RECRUITING)
- St. Jude Children's Research Hospital — Memphis, Tennessee, United States (RECRUITING)
- Cook Children's Medical Center — Fort Worth, Texas, United States (RECRUITING)
Study contacts
- Principal investigator: Charles Mullighan, MBBS, MD — St. Jude Children's Research Hospital
- Study coordinator: Charles Mullighan, MBBS, MD
- Email: charles.mullighan@stjude.org
- Phone: 901-595-3387
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Normal and Diseased Tissue and Body Fluids Samples, human biological samples, tissue banking