Collaborative care model for treating depression and anxiety

Collaborative Care for Treatment of Depression and Anxiety

Kaiser Permanente · NCT06556589

This study tests whether a new team-based approach to treating depression and anxiety over the phone can help patients at Kaiser Permanente Colorado feel better compared to those who don’t receive this type of care.

Quick facts

Study typeObservational
Enrollment200 (estimated)
Ages18 Years and up
SexAll
SponsorKaiser Permanente (other)
Locations1 site (Aurora, Colorado)
Trial IDNCT06556589 on ClinicalTrials.gov

What this trial studies

This project evaluates the effectiveness of a collaborative care model for primary care patients at Kaiser Permanente Colorado who have depression and/or anxiety. The approach involves evidence-based short-term treatments delivered via phone, utilizing automated processes for patient outreach and follow-up. A cluster randomized design will compare outcomes between clinics implementing collaborative care and those that are not, focusing on patient-centered team care, population-based outreach, and measurement-based treatment. The study aims to improve patient engagement and treatment outcomes through coordinated care efforts.

Who should consider this trial

Good fit: Ideal candidates are adults aged 18 and older with a recent diagnosis of depression or anxiety who are active members of the patient portal.

Not a fit: Patients currently engaged in behavioral health services or those with recent psychiatric hospitalizations may not benefit from this study.

Why it matters

Potential benefit: If successful, this model could significantly enhance treatment outcomes for patients suffering from depression and anxiety.

How similar studies have performed: Previous studies have shown promising results with collaborative care models in improving mental health outcomes, indicating that this approach is supported by existing evidence.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* 18+
* Current membership and active on patient portal
* Depression Diagnosis in the prior year
* Overdue for PHQ9 Screening based on the following criteria:

  * High Risk: Last PHQ9 screener was completed greater than 4 months ago AND total Score is greater than or equal 10 or item 9 is greater than 0.
  * Low Risk: Last PHQ9 screener was completed greater than 12 months ago AND Last PHQ9 Total Score is less than 10 and item 9 is equal to 0.
* Anxiety diagnoses in the prior year
* Has a baseline GAD7 in the same prior year; score = 10+ (\*Note: Provider referrals could be GAD7 score of 7 or higher)
* No Behavioral Health (BH) engagement in the prior year
* Patient is not in a Skilled Nursing Facility or Hospice
* Patient has no record of psychiatric hospitalization in the last year
* Patient does not need an interpreter (i.e., English speaking)
* Primary care location is one of the intervention clinics

Exclusion Criteria:

• Exclude individuals with any of the following diagnoses:

* Psychosis
* Dementia
* Bipolar
* Personality Disorders
* Post Traumatic Stress Disorder (PTSD)
* Obsessive Compulsive Disorder (OCD)
* Panic Disorder
* Cognitive Disorder

Where this trial is running

Aurora, Colorado

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Depression, Anxiety, Collaborative Care, Evaluation

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.