Cohort study of healthy pregnant women and their children's health
PRINCE - PRenatal Identification of Childrens HEalth
This study looks at how things like stress, medication, and nutrition during pregnancy affect the health and immunity of children from birth to age ten.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 1000 (estimated) |
| Ages | 18 Years to 50 Years |
| Sex | Female |
| Sponsor | Universitätsklinikum Hamburg-Eppendorf Academic / other |
| Locations | 1 site (Hamburg) |
| Trial ID | NCT05002023 on ClinicalTrials.gov |
What this trial studies
The PRINCE study recruits healthy and diseased pregnant women to assess the impact of prenatal challenges on their children's health and immunity. Participants are enrolled early in the first trimester and undergo various assessments, including clinical evaluations, sonographic examinations, and blood collection. The study aims to fill the gap in understanding how factors like stress, medication, and nutrition during pregnancy affect fetal development and long-term health outcomes in children. Follow-up assessments will track children's health and immunity from birth through the first ten years of life.
Who should consider this trial
Good fit: Ideal candidates for this study are pregnant women over 18 years of age with a singleton pregnancy who can provide informed consent.
Not a fit: Patients with multiple pregnancies, under 18 years of age, or those unable to give consent will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide insights into how prenatal factors influence children's health, potentially leading to improved maternal and child health interventions.
How similar studies have performed: Other observational studies have indicated the importance of prenatal factors on child health, suggesting that this approach could yield valuable insights.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Pregnant women * \>18 years of age * able to understand and sign the papers of consent * singleton pregnancy Exclusion Criteria: : * \<18 years of age * unable to give consent * multiple pregnancy * nicotine abuse * fetal aberration
Where this trial is running
Hamburg
- Universitätsklinikum Hamburg-Eppendorf — Hamburg, Germany (Recruiting)
Study contacts
- Principal investigator: Prof. Dr. Anke Diemert, MD — Department of Obstetrics and Fetal Medicine, Medical Center Hamburg-Eppendorf (UKE)
- Study coordinator: Prof. Dr. Anke Diemert, MD
- Email: a.diemert@uke.de
- Phone: 0049 +40 7410- 57832
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.