Cohort of tuberculosis patients at Avicenne Hospital
Tuberculosis Cohort Avicenne Hospital
This study is trying to gather information from tuberculosis patients at Avicenne Hospital to understand their treatment results and find ways to improve care for those with the disease.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 250 (estimated) |
| Ages | 18 Years to 80 Years |
| Sex | All |
| Sponsor | Assistance Publique - Hôpitaux de Paris Academic / other |
| Locations | 2 sites (Bobigny and 1 other locations) |
| Trial ID | NCT05539014 on ClinicalTrials.gov |
What this trial studies
This observational study aims to establish a cohort of patients diagnosed with tuberculosis at Avicenne Hospital in Seine-Saint-Denis, France, which has the highest incidence of the disease in the country. The study will recruit patients over a period of at least four years, followed by one year of monitoring, to gather data on treatment outcomes and patient characteristics. The goal is to identify factors associated with unfavorable treatment outcomes and develop strategies to improve tuberculosis control. This initiative is part of a broader effort to meet the WHO's targets for reducing tuberculosis incidence and mortality.
Who should consider this trial
Good fit: Ideal candidates for this study are newly diagnosed tuberculosis patients, either outpatients or inpatients, who are beginning treatment.
Not a fit: Patients who have been on anti-tuberculosis treatment for more than 7 days at the time of inclusion will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved treatment strategies and better control of tuberculosis, ultimately reducing its incidence and mortality rates.
How similar studies have performed: While this approach is novel in France, similar cohort studies in other regions have shown promise in understanding tuberculosis treatment outcomes.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Tuberculosis out- or in-patient newly treated in one of the inclusion centers for pulmonary or extra-pulmonary * Tu confirmed bacteriologically (direct examination, Gen-eXpert MTB/RIF and/or positive culture), suggestive histology (epithelioid gigantocellular granuloma with or without caseous necrosis), or strong clinical suspicion of tuberculosis, even if not yet biologically confirmed but with * A decision to introduce treatment. Exclusion Criteria: * opposition to participate in the study, anti-tuberculosis treatment for more than 7 days at the inclusion visit and participation in another research protocol.
Where this trial is running
Bobigny and 1 other locations
- Hopital Avicenne — Bobigny, France (Recruiting)
- Hôpital Avicenne — Bobigny, France (Not_yet_recruiting)
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.