Cohort of tuberculosis patients at Avicenne Hospital

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to establish a cohort of patients diagnosed with tuberculosis at Avicenne Hospital in Seine-Saint-Denis, France, which has the highest incidence of the disease in the country. The study will recruit patients over a period of at least four years, followed by one year of monitoring, to gather data on treatment outcomes and patient characteristics. The goal is to identify factors associated with unfavorable treatment outcomes and develop strategies to improve tuberculosis control. This initiative is part of a broader effort to meet the WHO's targets for reducing tuberculosis incidence and mortality.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Tuberculosis out- or in-patient newly treated in one of the inclusion centers for pulmonary or extra-pulmonary
* Tu confirmed bacteriologically (direct examination, Gen-eXpert MTB/RIF and/or positive culture), suggestive histology (epithelioid gigantocellular granuloma with or without caseous necrosis), or strong clinical suspicion of tuberculosis, even if not yet biologically confirmed but with
* A decision to introduce treatment.

Exclusion Criteria:

* opposition to participate in the study, anti-tuberculosis treatment for more than 7 days at the inclusion visit and participation in another research protocol.

Where it's running

• Hopital Avicenne
  Bobigny, France Recruiting
• Hôpital Avicenne
  Bobigny, France Not yet recruiting

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• FAP PET/CT in adults with pulmonary TB

  This early-phase study tests whether a FAP PET/CT scan can map lung fibrosis in adults with pulmonary TB before starting treatment and after cure.

  Recruiting Early Phase 1 University of Pennsylvania · Philadelphia, Pennsylvania · NCT07830771

• Sorfequiline-based regimens for adults with newly diagnosed drug-sensitive pulmonary TB

  This study tests two sorfequiline-containing regimens, each with pretomanid and linezolid, to see if they are safe and effective in adults with newly diagnosed drug-sensitive pulmonary TB.

  Recruiting at 6 sites Phase 2 Global Alliance for TB Drug Development · Wentworth, Durban and 11 other locations · NCT07672405

• Digital health tool to help more people start TB preventive therapy

  A digital health approach is being tested to see if it helps household and close contacts of people with drug-sensitive pulmonary TB start TB preventive therapy better.

  Recruiting at 8 sites Arba Minch University · Arba Minch, South Ethiopia and 13 other locations · NCT07313995

• Ear acupuncture to reduce nausea and vomiting from tuberculosis medicines

  This trial will test whether press-needle ear acupuncture can reduce nausea and vomiting in people taking medicines for pulmonary tuberculosis.

  Recruiting Universitas Indonesia · Jakarta, Jakarta Timur · NCT07271225

• 18F-FAPI-74 PET imaging for lung fibrosis in tuberculosis

  This project tries to see if 18F-FAPI-74 PET scans can detect lung fibrosis in adults with active or recently treated tuberculosis.

  Recruiting Children's Hospital Medical Center, Cincinnati · Cincinnati, Ohio · NCT07077213

• Blood TB DNA test to track treatment progress

  This project will test whether levels of TB-derived cell-free DNA in the blood can track treatment response in adults newly diagnosed with tuberculosis.

  Recruiting University of Oxford · Tak · NCT06845618

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.