Cohort of the Specialist Network Infectious Diseases: a large German patient data and biosample registry
Official title: Master Study Protocol for the Cohort of the Specialist Network Infectious Diseases (SNID)
Run by Goethe University · NCT06879184 · Data updated 2026-11-12
This observational cohort collects standardized clinical data and biosamples from adults with infectious diseases across German university hospitals to help test approaches for better diagnosis and treatment.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 15000 (estimated) |
| Sponsor | Goethe University Academic / other |
| Locations | 1 site (Frankfurt) |
| Status | Recruiting |
| Started | May 5, 2025 |
| Main results expected | June 30, 2030 |
| Study ends | June 30, 2030 |
| Registry record updated | September 29, 2026 |
| Trial ID | NCT06879184 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults (18+) hospitalized with respiratory, bloodstream, gastrointestinal, emerging, or CNS infections who can consent and comply with sample collection.
✕Probably not a fit
Patients who do not consent or who are hospitalized for non‑infectious conditions would not be eligible for benefit from participation.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
The SNID cohort links clinical information and pathogen biosamples in a standardized, quality‑assured framework for future research. It operates within the NUM network and uses a master protocol with modular sub‑studies focused on major infectious diseases. Participants are enrolled during hospitalization and followed at baseline and discharge, with additional visits as needed. The study supports pre‑screening of infection‑related hospitalizations to monitor pathogen changes and enable rapid responses to public health threats. It aims to enable translational research, pandemic preparedness, and sentinel surveillance of severe infections.
Why it matters
Potential benefit: If successful, this cohort could accelerate diagnostics and treatment strategies for infectious diseases and improve readiness for future outbreaks.
How similar studies have gone: Previous large infectious disease biobanks and sentinel networks have shown value in enabling translational research and outbreak monitoring; this project aims to build on those concepts within Germany.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Fulfillment of all inclusion and no exclusion criteria for at least one module * Ability to perform all baseline visit data and biosample collections according to the study requirements no later than 48 hours (with an additional 48-hour period for weekends) after fulfilling all study and specific module inclusion and exclusion criteria * Signed informed consent form from all patients capable of giving consent and understanding all contents of the informed consent * Age ≥ 18 years. Exclusion Criteria: There are no generic exclusion criteria in the master study protocol.
Where it's running
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University Hospital Frankfurt
Frankfurt, Germany Recruiting
Study contacts
- Study coordinator: Janne Vehreschild, Prof. Dr. med.
- Email: j.vehreschild@med.uni-frankfurt.de
- Phone: +49 151 17192218
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.