Cohort for predicting gastric cancer in patients with intestinal metaplasia
Official title: A Prospective Cohort Study for Gastric Cancer Prediction in Patients With Intestinal Metaplasia
Run by Seoul National University Hospital · NCT06075199 · Data updated 2026-11-12
This study is trying to see how intestinal metaplasia in patients might lead to gastric cancer over time by monitoring their health and collecting tissue samples.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 1000 (estimated) |
| Sponsor | Seoul National University Hospital Academic / other |
| Locations | 1 site (Seoul) |
| Status | Recruiting |
| Started | September 13, 2023 |
| Main results expected | June 30, 2033 |
| Study ends | June 30, 2033 |
| Registry record updated | November 29, 2024 |
| Trial ID | NCT06075199 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are patients who have been diagnosed with intestinal metaplasia during a prior endoscopy at Seoul National University Hospital.
✕Probably not a fit
Patients with a prior diagnosis of gastric cancer or adenoma, or those who have undergone gastrectomy, will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to establish a cohort of patients diagnosed with intestinal metaplasia to monitor the progression to gastric cancer over time. Patients at Seoul National University Hospital who have previously been diagnosed with intestinal metaplasia will undergo endoscopic procedures to collect tissue samples for histological analysis. These samples will be used to assess the severity of intestinal metaplasia and to identify potential biomarkers associated with the development of gastric cancer. Participants will be followed up with routine endoscopies to track any progression to cancer.
Why it matters
Potential benefit: If successful, this study could lead to the identification of biomarkers that help predict gastric cancer in at-risk patients.
How similar studies have gone: While similar studies have explored the relationship between intestinal metaplasia and gastric cancer, this specific cohort approach to identify predictive biomarkers is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients who visit Seoul National University Hospital * Patients who have been visually diagnosed with intestinal metaplasia at a prior exam Exclusion Criteria: * Patients who have been previously diagnosed with gastric cancer or adenoma * Patients who have previously received gastrectomy
Where it's running
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Seoul National University Hospital
Seoul, South Korea Recruiting
Study contacts
- Principal investigator: Soo-Jeong Cho, MD, PhD — Seoul National University Hospital
- Study coordinator: Soo-Jeong Cho, MD, PhD
- Email: crystal5@snu.ac.kr
- Phone: 02-2072-4073
Similar studies
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.