Cohort for predicting gastric cancer in patients with intestinal metaplasia
A Prospective Cohort Study for Gastric Cancer Prediction in Patients With Intestinal Metaplasia
This study is trying to see how intestinal metaplasia in patients might lead to gastric cancer over time by monitoring their health and collecting tissue samples.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 1000 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Seoul National University Hospital Academic / other |
| Locations | 1 site (Seoul) |
| Trial ID | NCT06075199 on ClinicalTrials.gov |
What this trial studies
This observational study aims to establish a cohort of patients diagnosed with intestinal metaplasia to monitor the progression to gastric cancer over time. Patients at Seoul National University Hospital who have previously been diagnosed with intestinal metaplasia will undergo endoscopic procedures to collect tissue samples for histological analysis. These samples will be used to assess the severity of intestinal metaplasia and to identify potential biomarkers associated with the development of gastric cancer. Participants will be followed up with routine endoscopies to track any progression to cancer.
Who should consider this trial
Good fit: Ideal candidates are patients who have been diagnosed with intestinal metaplasia during a prior endoscopy at Seoul National University Hospital.
Not a fit: Patients with a prior diagnosis of gastric cancer or adenoma, or those who have undergone gastrectomy, will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to the identification of biomarkers that help predict gastric cancer in at-risk patients.
How similar studies have performed: While similar studies have explored the relationship between intestinal metaplasia and gastric cancer, this specific cohort approach to identify predictive biomarkers is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients who visit Seoul National University Hospital * Patients who have been visually diagnosed with intestinal metaplasia at a prior exam Exclusion Criteria: * Patients who have been previously diagnosed with gastric cancer or adenoma * Patients who have previously received gastrectomy
Where this trial is running
Seoul
- Seoul National University Hospital — Seoul, South Korea (Recruiting)
Study contacts
- Principal investigator: Soo-Jeong Cho, MD, PhD — Seoul National University Hospital
- Study coordinator: Soo-Jeong Cho, MD, PhD
- Email: crystal5@snu.ac.kr
- Phone: 02-2072-4073
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.