Clinical trial Recruiting at 1 site Observational Ages 18 and up

Cohort for predicting gastric cancer in patients with intestinal metaplasia

Official title: A Prospective Cohort Study for Gastric Cancer Prediction in Patients With Intestinal Metaplasia

Run by Seoul National University Hospital · NCT06075199 · Data updated 2026-11-12

This study is trying to see how intestinal metaplasia in patients might lead to gastric cancer over time by monitoring their health and collecting tissue samples.

More Gastric Intestinal Metaplasia trials

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment1000 (estimated)
SponsorSeoul National University Hospital
Academic / other
Locations1 site (Seoul)
StatusRecruiting
StartedSeptember 13, 2023
Main results expectedJune 30, 2033
Study endsJune 30, 2033
Registry record updatedNovember 29, 2024
Trial IDNCT06075199 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are patients who have been diagnosed with intestinal metaplasia during a prior endoscopy at Seoul National University Hospital.

Probably not a fit

Patients with a prior diagnosis of gastric cancer or adenoma, or those who have undergone gastrectomy, will not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to establish a cohort of patients diagnosed with intestinal metaplasia to monitor the progression to gastric cancer over time. Patients at Seoul National University Hospital who have previously been diagnosed with intestinal metaplasia will undergo endoscopic procedures to collect tissue samples for histological analysis. These samples will be used to assess the severity of intestinal metaplasia and to identify potential biomarkers associated with the development of gastric cancer. Participants will be followed up with routine endoscopies to track any progression to cancer.

Why it matters

Potential benefit: If successful, this study could lead to the identification of biomarkers that help predict gastric cancer in at-risk patients.

How similar studies have gone: While similar studies have explored the relationship between intestinal metaplasia and gastric cancer, this specific cohort approach to identify predictive biomarkers is relatively novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients who visit Seoul National University Hospital
* Patients who have been visually diagnosed with intestinal metaplasia at a prior exam

Exclusion Criteria:

* Patients who have been previously diagnosed with gastric cancer or adenoma
* Patients who have previously received gastrectomy

Where it's running

  • Seoul National University Hospital
    Seoul, South Korea
    Recruiting

Study contacts

  • Principal investigator: Soo-Jeong Cho, MD, PhD — Seoul National University Hospital
  • Study coordinator: Soo-Jeong Cho, MD, PhD
  • Email: crystal5@snu.ac.kr
  • Phone: 02-2072-4073

Similar studies

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.