Coherent breathing combined with aerobic exercise for adults with stage 1 hypertension
Official title: Additional Effect of Coherent Breathing With Aerobic Exercise on Cardiopulmonary Parameters and Quality of Life in Stage 1 Hypertensive Individuals
Run by Foundation University Islamabad · NCT07573683 · Data updated 2026-11-12
See if adding coherent (slow, paced) breathing to regular aerobic exercise helps adults aged 30–65 with stage 1 hypertension lower blood pressure and improve heart and breathing measures.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 30 Years to 65 Years |
| Sex | All |
| Enrollment | 40 (estimated) |
| Sponsor | Foundation University Islamabad Academic / other |
| Locations | 1 site (Islamabad) |
| Status | Recruiting |
| Started | February 28, 2026 |
| Main results expected | May 15, 2026 |
| Study ends | May 15, 2026 |
| Registry record updated | May 7, 2026 |
| Trial ID | NCT07573683 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults 30–65 years old with stage 1 hypertension (130–139/80–89 mmHg), mild-to-moderate physical activity level, and the ability to follow instructions are ideal candidates.
✕Probably not a fit
People with uncontrolled hypertension, unstable cardiac disease, advanced coronary disease, significant lung disease, or major musculoskeletal/neurological limits are unlikely to benefit or be eligible.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This randomized controlled trial will enroll 40 adults aged 30–65 with stage 1 hypertension and assign them to aerobic exercise with coherent breathing or aerobic exercise alone for a 4-week program with five sessions per week. Cardiopulmonary measures (blood pressure, heart rate, respiratory rate, rate pressure product) and quality of life (MINICHAL questionnaire) will be recorded at baseline, 2 weeks, and after the program. The intervention compares the additive effect of a paced breathing technique (≈5–6 breaths/minute) when combined with standard aerobic sessions. Data will be analyzed using SPSS version 21.0 to determine whether the combined approach yields greater short-term improvements.
Why it matters
Potential benefit: If successful, the combined approach could offer a low-cost, non-drug way to lower blood pressure and improve cardiopulmonary function and quality of life for people with stage 1 hypertension.
How similar studies have gone: Prior small trials of slow or paced breathing and aerobic exercise have shown modest blood pressure and autonomic benefits, but large, longer randomized trials of coherent breathing added to exercise are limited.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Both male and female genders. * Adults aged 30-65 years. * Patients diagnosed with stage 1 hypertension 130-139/80-89mm Hg according to ACC/AHA 2017 guidelines. * Mild to moderate physical activity level on IPAQ questionnaire. * Individuals able to understand and follow the instructions. Exclusion Criteria: * Diagnosed uncontrolled hypertensive patients. * Unstable angina, MI, heart failure, advanced CAD patients, COPD, Asthma. * Severe neurological, musculoskeletal or gynecological conditions which limit participation in the study. * Recent history of fracture.
Where it's running
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Foundation University Islamabad
Islamabad, Pakistan Recruiting
Study contacts
- Study coordinator: Kainat Zahra, MSPT-CPPT
- Email: zahrakainat99@gmail.com
- Phone: 03367343005
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.