Cognitive training to improve emotion regulation in psychotic disorders
Official title: Cognitive Training for Emotion Regulation in Psychotic Disorders
Run by University of Georgia · NCT04414215 · Data updated 2026-11-12
This study is testing a smartphone app that provides cognitive training to see if it can help people with schizophrenia and schizoaffective disorder better manage their emotions.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 60 Years |
| Sex | All |
| Enrollment | 70 (estimated) |
| Sponsor | University of Georgia Academic / other |
| Locations | 1 site (Athens, Georgia) |
| Status | Recruiting |
| Started | June 1, 2020 |
| Main results expected | December 31, 2029 |
| Study ends | December 31, 2029 |
| Registry record updated | February 5, 2025 |
| Trial ID | NCT04414215 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include adults aged 18-60 diagnosed with schizophrenia or schizoaffective disorder who are clinically stable and speak English.
✕Probably not a fit
Patients with a history of intellectual disability, neurological disorders, or substance use disorders within the last six months may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study investigates the effectiveness of a cognitive training program aimed at enhancing emotion regulation in individuals with psychotic disorders, specifically schizophrenia and schizoaffective disorder. Participants will be randomly assigned to either an emotional working memory training group or a placebo group, with the intervention delivered via a smartphone app over 30 days. The study aims to assess whether this cognitive training can improve prefrontal activation and, consequently, emotion regulation abilities. The research addresses a significant gap in current therapeutic options for managing emotion regulation deficits in psychotic disorders.
Why it matters
Potential benefit: If successful, this intervention could provide a novel therapeutic approach to improve emotion regulation and overall functioning in patients with psychotic disorders.
How similar studies have gone: While cognitive training interventions have shown promise in other areas, this specific approach targeting emotion regulation in psychotic disorders is relatively novel and has not been extensively tested.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * diagnostic and statistical manual fifth edition diagnosis of schizophrenia or schizoaffective disorder * 18-60 years old * speaks English * premorbid intelligence quotient \> 70 * clinically stable as indicated by no antipsychotic medication changes in the last month or if on depot, no change in the past 2 months. Exclusion Criteria: * history of intellectual disability or neurological disorder * history of traumatic brain injury with loss of consciousness \> 10 minutes or behavioral sequelae * substance use disorder within the last 6 months (other than nicotine) * 4\) endorsement of MRI exclusion factors
Where it's running
-
University of Georgia
Athens, Georgia, United States Recruiting
Study contacts
- Study coordinator: Gregory P Strauss, PhD
- Email: gstrauss@uga.edu
- Phone: 706-542-0307
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.