Cognitive training program for survivors of hematopoietic cell transplantation
Official title: Intervention Strategies to Improve Cognitive Functioning in Hematologic Cancer Survivors After Hematopoietic Cell Transplantation
Run by University of Alabama at Birmingham · NCT03094026 · Data updated 2026-11-12
This study is testing a brain training program to see if it can help people who have survived hematopoietic cell transplantation think better and improve their memory over 12 weeks.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 21 Years and up |
| Sex | All |
| Enrollment | 60 (estimated) |
| Sponsor | University of Alabama at Birmingham Academic / other |
| Locations | 1 site (Birmingham, Alabama) |
| Status | Recruiting |
| Started | August 21, 2017 |
| Main results expected | July 2027 |
| Study ends | July 2027 |
| Registry record updated | April 20, 2026 |
| Trial ID | NCT03094026 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are English-speaking adults aged 21 and older who are outpatient survivors of allogeneic HCT performed at UAB, between 3 and 6 months post-transplant.
✕Probably not a fit
Patients with pre-existing neurological disorders, major psychiatric disorders, or significant sensory impairments may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This pilot study evaluates the feasibility of enrolling patients in a cognitive training intervention aimed at improving neurocognitive function in survivors of hematopoietic cell transplantation (HCT). Participants will use the Lumosity online cognitive training program, which includes various tasks designed to enhance processing speed, working memory, and executive function over a 12-week period. Additionally, the study will assess patients' interest in receiving genetic risk information related to cognitive impairment following HCT, exploring their attitudes towards genetic knowledge and its potential impact on treatment decisions.
Why it matters
Potential benefit: If successful, this intervention could enhance cognitive function in HCT survivors and improve their quality of life.
How similar studies have gone: While cognitive training interventions have been explored in various populations, this specific approach targeting HCT survivors is relatively novel and has not been extensively tested.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * ≥ 21 years old at time of allogeneic HCT performed at UAB * Outpatient and between 3 and 6 months post HCT * English speaking * Possess access to an internet-connected home computer Exclusion criteria: * History of pre-existing neurological disorder or documented major psychiatric disorder; significant auditory, visual, or motor impairments * Participated in neuropsychological intervention within the past 6 months * History of color blindness
Where it's running
-
University of Alabama at Birmingham
Birmingham, Alabama, United States Recruiting
Study contacts
- Principal investigator: Noha M Sharafeldin — University of Alabama at Birmingham
- Study coordinator: Noha M Sharafeldin, MD,MSc, PhD
- Email: nsharaf@uab.edu
- Phone: 2056382144
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.