Clinical trial Recruiting at 1 site Interventional Ages 21 and up

Cognitive training program for survivors of hematopoietic cell transplantation

Official title: Intervention Strategies to Improve Cognitive Functioning in Hematologic Cancer Survivors After Hematopoietic Cell Transplantation

Run by University of Alabama at Birmingham · NCT03094026 · Data updated 2026-11-12

This study is testing a brain training program to see if it can help people who have survived hematopoietic cell transplantation think better and improve their memory over 12 weeks.

Quick facts

Study typeInterventional
Ages21 Years and up
SexAll
Enrollment60 (estimated)
SponsorUniversity of Alabama at Birmingham
Academic / other
Locations1 site (Birmingham, Alabama)
StatusRecruiting
StartedAugust 21, 2017
Main results expectedJuly 2027
Study endsJuly 2027
Registry record updatedApril 20, 2026
Trial IDNCT03094026 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are English-speaking adults aged 21 and older who are outpatient survivors of allogeneic HCT performed at UAB, between 3 and 6 months post-transplant.

Probably not a fit

Patients with pre-existing neurological disorders, major psychiatric disorders, or significant sensory impairments may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This pilot study evaluates the feasibility of enrolling patients in a cognitive training intervention aimed at improving neurocognitive function in survivors of hematopoietic cell transplantation (HCT). Participants will use the Lumosity online cognitive training program, which includes various tasks designed to enhance processing speed, working memory, and executive function over a 12-week period. Additionally, the study will assess patients' interest in receiving genetic risk information related to cognitive impairment following HCT, exploring their attitudes towards genetic knowledge and its potential impact on treatment decisions.

Why it matters

Potential benefit: If successful, this intervention could enhance cognitive function in HCT survivors and improve their quality of life.

How similar studies have gone: While cognitive training interventions have been explored in various populations, this specific approach targeting HCT survivors is relatively novel and has not been extensively tested.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* ≥ 21 years old at time of allogeneic HCT performed at UAB
* Outpatient and between 3 and 6 months post HCT
* English speaking
* Possess access to an internet-connected home computer

Exclusion criteria:

* History of pre-existing neurological disorder or documented major psychiatric disorder; significant auditory, visual, or motor impairments
* Participated in neuropsychological intervention within the past 6 months
* History of color blindness

Where it's running

  • University of Alabama at Birmingham
    Birmingham, Alabama, United States
    Recruiting

Study contacts

  • Principal investigator: Noha M Sharafeldin — University of Alabama at Birmingham
  • Study coordinator: Noha M Sharafeldin, MD,MSc, PhD
  • Email: nsharaf@uab.edu
  • Phone: 2056382144

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.