Cognitive multi-sensory rehabilitation for improving upper limb function and reducing fatigue in stroke patients

Cognitive Multi-sensory Rehabilitation on Upper Limb Functions and Fatigue in Different Grades of Spasticity in Stroke Patients

Not applicable Interventional Cairo University · NCT06251661

This study is testing if a new therapy that combines cognitive exercises with regular physical therapy can help stroke patients improve their arm movement and reduce fatigue.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment40 (estimated)
Ages45 Years to 65 Years
SexMale
SponsorCairo University Academic / other
Locations1 site (Cairo, Giza)
Trial IDNCT06251661 on ClinicalTrials.gov

What this trial studies

This interventional study investigates the effectiveness of Cognitive Multi-sensory Rehabilitation (CMR) on enhancing upper limb function and alleviating fatigue in chronic stroke patients. Participants will be divided into two groups, with one receiving CMR combined with traditional physical therapy, while the control group will only receive traditional physical therapy. The intervention consists of 12 sessions over four weeks, focusing on sensory discrimination exercises and cognitive engagement to improve motor recovery. The study aims to address the significant barriers posed by post-stroke fatigue and impaired motor function.

Who should consider this trial

Good fit: Ideal candidates are individuals aged 45 to 65 who are 6-18 months post-ischemic stroke and living in the community.

Not a fit: Patients with severe spasticity, other neurological conditions, or significant upper extremity pain may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could significantly improve upper limb function and reduce fatigue in stroke patients, enhancing their quality of life.

How similar studies have performed: Preliminary evidence suggests that sensory rehabilitation approaches have shown promise in enhancing motor recovery in stroke patients, indicating potential success for this novel method.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age between 45 and 65 years.
* 6-18 months after ischemic stroke
* living in the community (i.e., not in a long-term care home).
* medically stable.
* normal score in the Montreal Cognitive Assessment (MoCA: 25 to 30, maximum score = 30).
* Spasticity of upper limb muscles ranged from (grade 1:2) according to the Modified Ashworth scale.

Exclusion Criteria:

* severe spasticity (Modified Ashworth Scale score of 4)
* any medical condition that hinders full participation,
* another neurological diagnosis beyond stroke including cognitive impairment, or
* upper extremity pain \> 4/10 on the Numeric Pain Rating Scale (maximum 10/10).

Where this trial is running

Cairo, Giza

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions StrokeIschemicCMRupper limb functionfatigue
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.