Cognitive-behavioral therapy for COVID-19 survivors with mental health issues

Evaluate the Effectiveness for Long-term Consequences of COVID-19 of Mindfulness-based Stress Reduction (MBSR)

Not applicable Interventional Azienda Socio Sanitaria Territoriale di Lecco · NCT05815693

This study is testing if combining mindfulness and therapy with regular medication can help COVID-19 survivors who are struggling with mental health issues feel better over a year.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment140 (estimated)
SexAll
SponsorAzienda Socio Sanitaria Territoriale di Lecco Academic / other
Locations1 site (Lecco)
Trial IDNCT05815693 on ClinicalTrials.gov

What this trial studies

This clinical trial evaluates the effectiveness of mindfulness-based stress reduction (MBSR) and cognitive behavioral therapy (CBT) for COVID-19 survivors who have been discharged from the intensive care unit and are experiencing psychological consequences such as chronic pain, anxiety, depression, and insomnia. Participants will be randomly assigned to either receive standard pharmacological therapy or the experimental group that includes psychotherapy alongside their medication. The study will assess the long-term effects of these interventions over a 12-month period using various rating scales to measure improvements in mental health and quality of life.

Who should consider this trial

Good fit: Ideal candidates are COVID-19 survivors who were hospitalized in intensive care and are currently experiencing chronic pain, anxiety, depression, or insomnia while on pharmacological therapy.

Not a fit: Patients who are not on pharmacological therapy for their mental health issues or were not hospitalized in intensive care for COVID-19 may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could significantly improve the mental health and overall well-being of COVID-19 survivors.

How similar studies have performed: While there is emerging evidence supporting the use of psychological therapies for post-COVID conditions, this specific approach combining MBSR and CBT in this population is relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Intensive care survivors
* Surviving COVID-19 patients
* Patients with Chronic Pain Anxiety Depression and/or Insomnia in drug therapy

Exclusion Criteria:

* Patients with Chronic Pain Anxiety Depression and/or Insomnia NOT in drug therapy
* Patients not hospitalized in intensive care for COVID-19

Where this trial is running

Lecco

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Post Acute COVID-19 Syndrome
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.