Cognitive and physical training for patients with COPD
Feasibility of a Home-Based Cognitive-Physical Exercise Program in Chronic Obstructive Pulmonary Disease (COPD) Patients: a Pilot Randomized Controlled Trial
This study is testing a new 8-week home program that combines brain exercises and physical training to see if it helps people with moderate to severe COPD feel better and improve their daily lives.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 24 (estimated) |
| Ages | 50 Years and up |
| Sex | All |
| Sponsor | University Health Network, Toronto Academic / other |
| Locations | 1 site (Toronto, Ontario) |
| Trial ID | NCT05140226 on ClinicalTrials.gov |
What this trial studies
This research evaluates the feasibility and efficacy of an 8-week home-based cognitive-physical training program for patients with moderate to severe Chronic Obstructive Pulmonary Disease (COPD). Participants will be randomly assigned to either a cognitive-physical training group or a physical training group, with interventions conducted remotely. The study aims to assess adherence, satisfaction, and the impact of the training on cognitive performance, physical function, and overall quality of life. Weekly follow-up video calls will ensure participant engagement and monitor progress.
Who should consider this trial
Good fit: Ideal candidates are adults aged 50 and older with a clinical diagnosis of COPD who can mobilize independently and have access to a reliable internet connection.
Not a fit: Patients currently participating in a pulmonary rehabilitation program or those with severe cognitive impairments or other significant health issues may not benefit from this study.
Why it matters
Potential benefit: If successful, this program could significantly enhance cognitive and physical performance in COPD patients, improving their daily functioning and quality of life.
How similar studies have performed: Previous studies have shown success in cognitive training for improving cognitive performance, but this combined approach in COPD patients is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adult participants (≥ 50 years of age) * Clinical and spirometric diagnosis of COPD (FEV1 30-80%) * Access to reliable internet connection * Ability to mobilize independently and safely, with or without a walking aid Exclusion Criteria: * Current participation in a pulmonary rehabilitation program * Disease exacerbation in the past 3 months * Diagnosis of a neurological or musculoskeletal condition that would interfere with safe performance of study tests (e.g., stroke, myopathy, inflammatory arthritis) * Severe cognitive impairment ascertained by chart review or self-reported * Coronary artery disease, pacemaker or implantable defibrillator, clinical diagnosis of congestive heart failure (CHF), or poorly controlled arrhythmias * Medical instability (hepatic dysfunction, metabolic abnormalities, or active infection) * Overt psychiatric disorder or substance abuse * Patient on home oxygen therapy * Insufficient English fluency and cognition to carry out testing and training * Patient actively listed for lung transplantation
Where this trial is running
Toronto, Ontario
- University Health Network — Toronto, Ontario, Canada (Recruiting)
Study contacts
- Principal investigator: Dmitry Rozenberg, MD PhD — University Health Network, Toronto
- Study coordinator: Dmitry Rozenberg, MD, PhD
- Email: Dmitry.Rozenberg@uhn.ca
- Phone: 416-340-4800
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.