Clinical trial Recruiting at 1 site Interventional Ages 40 to 65

CO-OP to improve daily tasks and executive skills after stroke

Official title: Effects of the Cognitive Orientation to Daily Occupational Performance (CO-OP) Approach on Occupational Performance and Executive Function in Adults With Stroke: A Randomised Controlled Trial

Run by Hacettepe University · NCT07127536 · Data updated 2026-11-12

This program will try the CO-OP method with adults who have had a stroke to see if it helps them do everyday tasks more easily and improves planning and attention.

More Stroke trials

Quick facts

Study typeInterventional
Ages40 Years to 65 Years
SexAll
Enrollment66 (estimated)
SponsorHacettepe University
Academic / other
Locations1 site (Ankara)
StatusRecruiting
StartedJanuary 1, 2024
Main results expectedDecember 31, 2025
Study endsJune 1, 2026
Registry record updatedAugust 22, 2025
Trial IDNCT07127536 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are adults 3 months to 2 years after a first-ever stroke, with Brunnstrom stage 2 or higher, able to read and write, and receiving rehabilitation at Etlik City Hospital.

Probably not a fit

Patients with moderate to severe aphasia, significant cognitive impairment (MMSE ≤ 24), other major orthopedic, psychological, or neurological conditions, or those not receiving care at the study site are unlikely to benefit from this program.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This randomized study compares standard occupational therapy alone versus standard therapy plus the Cognitive Orientation to Daily Occupational Performance (CO-OP) approach in adults in the subacute phase after stroke. Participants are randomly assigned to receive CO-OP sessions (45 minutes per session, five days a week for four weeks) in addition to usual occupational therapy or to receive usual occupational therapy alone. Researchers will measure changes in real-life daily activity performance and executive functions such as planning and attention before and after the intervention. The trial enrolls first-ever stroke patients who can read and write and are receiving rehabilitation at Etlik City Hospital in Ankara.

Why it matters

Potential benefit: If successful, CO-OP could help stroke survivors regain independence in meaningful daily tasks and strengthen planning and attention skills.

How similar studies have gone: CO-OP has shown promise in improving task performance and executive function in rehabilitation studies, but randomized evidence specifically in subacute adult stroke populations remains limited.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Being in the subacute phase after stroke (3 months \< stroke onset \< 2 years)
* First-ever stroke
* Brunnstrom stage 2 or above
* Ability to read and write
* Receiving rehabilitation services at Ankara Etlik City Hospital, Physical Medicine and Rehabilitation Hospital

Exclusion Criteria:

* Having any orthopedic, psychological, or neurological disorder other than stroke
* Having moderate to severe aphasia
* Having cognitive impairment (Mini-Mental State Examination score ≤ 24)
* Not willing to participate in the study

Where it's running

  • Etlik City Hospital
    Ankara, Turkey (Türkiye)
    Recruiting

Similar studies

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.