Closed-loop spinal cord stimulation for treating complex regional pain syndrome

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to evaluate the effectiveness of closed-loop spinal cord stimulation in patients with complex regional pain syndrome (CRPS) by comparing outcomes between those in the acute/subacute phase and those in the chronic phase. Participants will be divided into two groups based on the timing of their symptoms and will undergo a 7-day trial with a temporary spinal cord stimulator. If the device shows improvement in pain and function, a permanent device will be implanted. Patients will complete outcome assessments at baseline, after the trial, and at 3 and 6 months, along with blood tests to measure prolactin levels associated with pain and stress.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* 18 years or older
* neuromodulation naive patients with unilateral CRPS type 1 or type 2 (defined by Budapest Criteria)
* pre-procedure psychological clearance

Exclusion Criteria:

* younger than 18 years
* prior neuromodulation including spinal cord stimulation
* prior dorsal root ganglion stimulation
* prior peripheral nervous system stimulation
* anatomical obstacles to dorsal column lead placement

Where it's running

• Scripps Clinic Torrey Pines
  La Jolla, California, United States Recruiting

Study contacts

• Principal investigator: David B Hiller, MD — Physician
• Study coordinator: Julie C McCauley
• Email: mccauley.julie@scrippshealth.org
• Phone: 585-554-7122

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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• Using infrared imaging to assess spinal cord stimulation effects in CRPS patients

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• Compression garments for upper-limb pain in complex regional pain syndrome

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• New technology for deep brain stimulation to treat chronic pain

  This study is testing a new type of brain stimulation to see if it can help people with chronic pain that doesn't respond to regular treatments.

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.