Clonidine added to ultrasound-guided rectus sheath block for outpatient umbilical hernia repair

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a prospective, randomized, double-blind trial comparing bilateral ultrasound-guided rectus sheath block (RSB) with and without clonidine as the sole anesthetic technique for elective ambulatory umbilical hernioplasty. Adults aged 18–65 with ASA I–II and hernia defects ≤4 cm are randomized to receive identical volumes of local anesthetic with or without 75 mcg clonidine per side under real-time ultrasound guidance. Sedation is given as needed and standard monitoring is used; outcomes include intraoperative and postoperative pain scores, recovery quality, opioid requirements, and side effects recorded up to 48 hours after surgery. The trial is conducted at the ambulatory surgery unit of the Policlínica Universitária Piquet Carneiro in Rio de Janeiro and uses patient questionnaires and clinical monitoring to compare groups.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Adults aged 18 to 65 years;
* Both male and female participants;
* ASA physical status I or II (American Society of Anesthesiologists classification);
* Scheduled for elective ambulatory umbilical hernia repair;
* Hernial defect size ≤ 4 cm (small to medium).

Exclusion Criteria:

* Refusal or inability to provide written informed consent;
* Cognitive or psychiatric disorders that impair comprehension or adherence to the study protocol;
* Known allergy or hypersensitivity to local anesthetics, clonidine, opioids, nonsteroidal anti-inflammatory drugs (NSAIDs), or other analgesics;
* Participation in another clinical trial within the previous 30 days;
* Missing data or loss to follow-up during postoperative assessments;
* Contraindications to regional anesthesia or known coagulopathy.

Where it's running

• Policlinica Universitária Piquet Carneiro
  Rio de Janeiro, Rio de Janeiro, Brazil Recruiting

Study contacts

• Study coordinator: Samuel N Abreu, MD
• Email: samuel.abreu@ppc.uerj.br
• Phone: 55 21 987901911

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Low-Volume PENG Block With Dexamethasone After Hip Replacement

  This trial tests whether a smaller PENG block with dexamethasone provides similar pain relief but preserves quadriceps strength after hip replacement, compared with the standard-volume PENG block.

  Recruiting Phase 4 Ain Shams University · Cairo, Cairo Governorate · NCT07855341

• Analgesia after open inguinal hernia repair using intrathecal morphine or a transversalis fascia plane block

  This trial tests whether intrathecal morphine or a ultrasound-guided transversalis fascia plane block can provide better pain relief after open inguinal hernia repair in adults.

  Recruiting Atatürk Chest Diseases and Chest Surgery Training and Research Hospital · Yenimahalle, Ankara · NCT07826741

• Single-level vs two-level erector spinae plane block for breast surgery

  This study tests whether a single-level ESPB provides similar pain relief to a two-level ESPB for adults undergoing breast surgery.

  Recruiting Atatürk Chest Diseases and Chest Surgery Training and Research Hospital · Yenimahalle, Ankara · NCT07747623

• Transverse vs Longitudinal Serratus Anterior Plane Block for Breast Surgery

  This trial tests whether a longitudinal ultrasound view for serratus anterior plane block provides better pain relief after breast surgery than the standard transverse view.

  Recruiting Ankara Etlik City Hospital · Ankara, Yenimahalle\Ankara · NCT07739277

• iPAWS: Helping teens manage pain and risky behaviors after wisdom tooth removal

  This program tests a short online intervention to help teens and their parents handle post-surgical pain and reduce risky behaviors after wisdom tooth extraction.

  Recruiting Brown University · Providence, Rhode Island · NCT07731295

• Single-shot nerve block with IV dexamethasone for rebound pain after shoulder surgery

  This trial tests whether giving a one-time shoulder nerve block plus an IV dexamethasone dose can prevent rebound pain after shoulder surgery.

  Recruiting Phase 4 Seoul National University Hospital · Seoul, Jongno-gu · NCT07699744

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.