Clinical features and molecular drivers of obstructive sleep apnea

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational project will enroll patients with suspected obstructive sleep apnea at the sleep center of Beijing Chaoyang Hospital and build a multi-omics database from clinical data and biological samples. Investigators will compare immune, metabolic, and outcome patterns across different OSA severity levels and follow participants for at least one year to document prognosis, complications, and comorbidities. The study aims to track immune and metabolic dynamics after treatment and to identify biomarkers and potential therapeutic targets associated with OSA. Participants must consent to sample collection and follow-up, while those with major organ failure, pregnancy/lactation, or inability to comply with follow-up are excluded.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients with suspected obstructive sleep apnea (OSA) admitted to the sleep center of the respiratory Department of Beijing Chaoyang Hospital, Capital Medical University.
* Volunteer to participate in the study and sign an informed consent, and can complete at least 1 year of follow-up.

Exclusion Criteria:

* Patients with obstructive sleep apnea who have been treated with impermanent positive pressure ventilation;
* Pregnant or lactating women;
* Patients with severe respiratory failure requiring mechanical ventilation;
* Patients with severe heart, lung, liver, kidney, and central nervous system damage;
* Refuse to participate in follow-up visits and/or take biological samples.

Where it's running

• Beijing Chaoyang hospital affiliated to Capital Medical University
  Beijing, Beijing Municipality, China Recruiting

Study contacts

• Study coordinator: Zhiling Zhao
• Email: cysleep@163.com
• Phone: +86 186 1280 8859

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Other studies for the same condition or treatment. Recruiting studies are listed first.

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.