Classifying individuals at risk for cervical cancer

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to analyze genomic risk factors associated with cervical cancer and classify individuals into different risk categories. By utilizing genome-wide association studies, the research will identify genetic markers linked to susceptibility to cervical cancer. Participants will undergo screening colposcopy and provide blood samples for PCR and sequencing to explore potential biomarkers and therapeutics. The study will follow participants for five years to monitor outcomes and validate findings.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Subjects aged \>=18 years at time of consent
2. Intended to undergo screening colposcopy
3. Considered by a physician or healthcare provider as being of "average risk" for cervical cancer
4. Willing to consent to blood draw cervical disease treatments
5. Willing to sonsent to follow-up for five years as per protocol

Exclusion Criteria:

1. History of cervical cancer
2. History of any malignancy (patients who have undergone surgical removal of skin squamous cell cancer may be enrolled provided the procedure was completed at least 12 months prior to the date of provision of informed consent for the study)
3. Currently taking any anti-neoplastic or disease-modifying anti-rheumatic drugs.
4. Any major physical trauma (e.g. disruption of tissue, surgery, organ transplant, blood product transfusion) within the 30 days leading up to the provision of informed consent
5. Known medical condition which, in the opinion of the investigator, should preclude enrollment into the study

Where it's running

• The First Affiliated Hospital of USTC
  Hefei, Anhui, China Recruiting

Study contacts

• Study coordinator: Yingying Wang, Doctor
• Email: yingyingwang@ustc.edu.cn
• Phone: 18652270921

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.