Circuit training to improve muscle mass and quality of life in postmenopausal women

The Effects of Short-Term Circuit Strength Training Intervention on Muscle Mass, Metabolic Health, Balance, Quality of Life, and Inflammaging in Sedentary Postmenopausal Women

Not applicable Interventional Loma Linda University · NCT06445842

This study tests if a 10-week circuit training program can help sedentary postmenopausal women gain muscle, improve their strength and balance, and enhance their overall quality of life.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment46 (estimated)
Ages50 Years to 75 Years
SexAll
SponsorLoma Linda University Academic / other
Locations1 site (Loma Linda, California)
Trial IDNCT06445842 on ClinicalTrials.gov

What this trial studies

This research investigates the effects of short-term circuit strength training on muscle mass, strength, balance, functional capacity, and quality of life in sedentary postmenopausal women. The study employs a randomized controlled trial design and utilizes various assessment tools, including body composition measurements, grip strength tests, and questionnaires to evaluate psychosocial factors. Participants will undergo a 10-week intervention, with initial and final data collection to assess the impact of the exercise program.

Who should consider this trial

Good fit: Ideal candidates are sedentary females aged 50 to 75 years who are postmenopausal and physically capable of participating in exercise.

Not a fit: Patients who are already moderately to highly active or have health conditions contraindicating physical exercise may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could enhance physical and psychosocial well-being in postmenopausal women through improved muscle mass and quality of life.

How similar studies have performed: Other studies have shown positive outcomes with exercise interventions in similar populations, suggesting potential for success in this approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Females aged between 50 and 75 years.
* Self-reported postmenopausal status (i.e., cessation of menstruation for a minimum of 12 months).
* Physically capable of participating in an exercise intervention.
* No engagement in structured resistance or aerobic training programs in the six months preceding the study.

Exclusion Criteria:

* Classification as moderate and highly active on the International Physical Activity Questionnaire (IPAQ) (600-3000 MET-minutes/week for "moderate" and higher than 3000 MET-minutes/week for "high" score)
* Diagnosis of any health condition that constitutes a contraindication to physical exercise (e.g., significant cardiovascular disease, orthopedic or neuromuscular restrictions impacting exercise performance or safety).
* Regular use of medication with the potential to affect study outcomes (e.g., corticosteroids, immunosuppressants).

Where this trial is running

Loma Linda, California

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Postmenopausalpostmenopausalbalance
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.