Ciprofol infusion for anesthesia in thoracoscopic lobectomy
Effect of Ciprofol Infusion for Induction and Maintenance on Hemodynamics and Postoperative Recovery in Patients Undergoing Thoracoscopic Lobectomy : a Randomized, Controlled Trial
This study is testing whether a new anesthesia drug called ciprofol can help people aged 18 to 65 have better blood pressure and heart rate control, as well as a smoother recovery, during and after thoracoscopic lung surgery compared to the usual drug, propofol.
Quick facts
| Phase | Phase 4 |
|---|---|
| Study type | Interventional |
| Enrollment | 126 (estimated) |
| Ages | 18 Years to 65 Years |
| Sex | All |
| Sponsor | Qianfoshan Hospital Academic / other |
| Locations | 1 site (Jinan, Shandong) |
| Trial ID | NCT05664386 on ClinicalTrials.gov |
What this trial studies
This clinical trial investigates the effects of ciprofol infusion compared to propofol on hemodynamics and postoperative recovery in patients undergoing thoracoscopic lobectomy. Patients aged 18 to 65 are randomly assigned to receive either ciprofol or propofol during anesthesia induction and maintenance. The study measures fluctuations in hemodynamic parameters such as blood pressure and heart rate throughout the procedure. The goal is to determine if ciprofol provides better stability and recovery outcomes than traditional anesthetics.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18-65 with a BMI of 20-30 scheduled for thoracoscopic lobectomy under general anesthesia.
Not a fit: Patients with airway difficulties, allergies to study drugs, or those with mental health issues may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved hemodynamic stability and faster recovery for patients undergoing thoracoscopic lobectomy.
How similar studies have performed: Other studies have shown promising results with similar anesthetic approaches, but the specific use of ciprofol in this context is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * American Society of Anesthesiology (ASA)Ⅰ～Ⅱ grade; * 18-65 years; * Body mass index (BMI) 20-30kg/m2 ; * Scheduled for thoracoscopic lobectomy under general anesthesia; Exclusion Criteria: * Refused to participate in the clinical study; * Predictable airway difficulties requiring awake intubation; * Allergy to the drugs which were used in this study; * Tracheal intubation failed for twice; * Patients with mental diseases or consciousness disorder; * long-term use of sedatives or Antidepressants; * Patients who are participating in other clinical studies.
Where this trial is running
Jinan, Shandong
- Department of Anesthesiology, The First Affiliated Hospital of Shandong First Medical University & Shandong Provincial Qianfoshan Hospital — Jinan, Shandong, China (Recruiting)
Study contacts
- Study coordinator: NA GUO, Doctor
- Email: xinzangbianshu@163.com
- Phone: 18615605135
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.