Chronic thromboembolic pulmonary hypertension after pulmonary embolism

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is an observational cohort of adults with recent acute pulmonary embolism who meet higher-risk PESI/sPESI criteria, followed to detect incident CTEPH. Participants undergo baseline clinical evaluation and transthoracic Doppler echocardiography with attention to RV function and specific Doppler signs, and are followed for imaging or clinical confirmation of CTEPH. Patients with secondary causes of pulmonary hypertension, severe renal or hepatic impairment, or contraindications to anticoagulation are excluded. The primary goal is to predict CTEPH occurrence in symptomatic post-PE patients using clinical and echocardiographic markers.

Why it matters

Who can join: the full rules

Inclusion Criteria:

Any patient diagnosed as acute pulmonary embolism ,aged between 18-80 years old which Pulmonary Embolism Severity Index (PESI) class III-V or sPESI ≥1,

Exclusion Criteria:

Secondary causes for pulmonary hypertension Severe kidney injury(eGFR\>30 mg/dl/1.7m2) Hepatic affection Contraindication to anti-coagulation

Where it's running

• Assiut University
  Asyut, Egypt Recruiting

Study contacts

• Principal investigator: Ester A Faried, Resident — Assiut University
• Study coordinator: Ester A Faried, resident
• Email: esterashraf1810@gmail.com
• Phone: 01277194352

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Pulmonary Embolism Registry from Emergency Care to Long-Term Follow-Up

  This registry follows adults with acute pulmonary embolism to see how care is given in the real world and what happens over time.

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• Nailfold Capillaroscopy in Pulmonary Hypertension

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• How pulmonary endarterectomy affects confidence in managing chronic thromboembolic pulmonary hypertension

  This project will see if pulmonary endarterectomy helps people with chronic thromboembolic pulmonary hypertension feel more confident managing their condition.

  Recruiting Damascus University · Damascus, Rif-dimashq Governorate · NCT07272798

• Registry of people with chronic thromboembolic pulmonary hypertension in Russia

  This registry collects health, history, and treatment information from people in Russia with chronic thromboembolic pulmonary hypertension to see which factors relate to their prognosis.

  Recruiting National Medical Research Center for Cardiology, Ministry of Health of Russian Federation · Moscow · NCT07254078

• Effects of stopping riociguat on heart function in patients with CTEPH

  This study is testing how stopping the medication riociguat affects heart function in patients with inoperable CTEPH who have had balloon pulmonary angioplasty.

  Recruiting at 3 sites Phase 3 Beijing Chao Yang Hospital · Beijing, China and 2 other locations · NCT06922240

• Switching from Sildenafil to Riociguat for CTEPH Patients

  This study is testing if switching from sildenafil to riociguat can help people with Chronic Thromboembolic Pulmonary Hypertension feel better after they’ve already had balloon pulmonary angioplasty.

  Recruiting Phase 4 Chinese University of Hong Kong · Hong Kong · NCT06715280

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.