CHRIST program to improve upper arm function in children after stroke
Effects of Comprehensive Hand Repetitive Intense Strength Training on Upper Limb Function in Children With Pediatric Stroke
We will try the CHRIST hand-strength and repetitive training program to see if it improves upper arm use in children aged 7–12 who had a stroke.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 15 (estimated) |
| Ages | 7 Years to 12 Years |
| Sex | All |
| Sponsor | Riphah International University Academic / other |
| Locations | 1 site (Mandi Bahāuddīn, Punjab Province) |
| Trial ID | NCT07441057 on ClinicalTrials.gov |
What this trial studies
This interventional study delivers Comprehensive Hand Repetitive Intensive Strength Training (CHRIST), a high-repetition, strength-based, goal-oriented therapy targeting upper limb coordination and use in pediatric stroke survivors. Children aged 7–12 with clinical upper limb motor impairment receive structured therapy sessions and their manual ability is measured before and after the intervention using the ABILHAND-Kids questionnaire. Participants with recent intensive upper limb therapy, uncontrolled seizures, severe cognitive/behavioral impairments, or orthopedic limitations are excluded. The study is conducted at clinical sites that treat pediatric stroke patients in Mandi Bahāuddīn, Punjab Province.
Who should consider this trial
Good fit: Children aged 7–12 with a history of ischemic or hemorrhagic pediatric stroke and clinical upper limb motor impairment who can attend therapy and whose parents/guardians provide consent.
Not a fit: Children with severe cognitive or behavioral problems, uncontrolled seizures, recent intensive upper limb therapy, or orthopedic conditions limiting arm movement may not benefit or be eligible.
Why it matters
Potential benefit: If successful, CHRIST could improve hand function and everyday arm use, helping affected children gain more independence in daily activities.
How similar studies have performed: High-repetition, goal-directed hand training has shown benefit in related populations such as pediatric cerebral palsy and adult stroke, but pediatric stroke–specific evidence remains limited.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Children aged 7 to 12 years diagnosed with pediatric ischemic or hemorrhagic stroke(21). * Clinical evidence of upper limb motor impairment following stroke. * Parent/guardian consent and child assent obtained. Exclusion Criteria: * Severe cognitive or behavioral impairments interfering with therapy. * Uncontrolled seizures or medical conditions contraindicating exercise. * Previous participation in intensive upper limb therapy within the last 3 months. * Orthopedic conditions (e.g., fractures, contractures) that limit upper limb movement.
Where this trial is running
Mandi Bahāuddīn, Punjab Province
- Clinical settings having pediatric stroke patients. — Mandi Bahāuddīn, Punjab Province, Pakistan (Recruiting)
Study contacts
- Principal investigator: Mashar Hayat, MS — Riphah International University, Lahore
- Study coordinator: Imran Amjad, Phd
- Email: imran.amjad@riphah.edu.pk
- Phone: 03324390125
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.