Clinical trial Recruiting at 1 site Interventional Ages 7 to 12

CHRIST program to improve upper arm function in children after stroke

Official title: Effects of Comprehensive Hand Repetitive Intense Strength Training on Upper Limb Function in Children With Pediatric Stroke

Run by Riphah International University · NCT07441057 · Data updated 2026-11-12

We will try the CHRIST hand-strength and repetitive training program to see if it improves upper arm use in children aged 7–12 who had a stroke.

Quick facts

Study typeInterventional
Ages7 Years to 12 Years
SexAll
Enrollment15 (estimated)
SponsorRiphah International University
Academic / other
Locations1 site (Mandi Bahāuddīn, Punjab Province)
StatusRecruiting
StartedFebruary 4, 2026
Main results expectedJuly 30, 2026
Study endsAugust 30, 2026
Registry record updatedFebruary 27, 2026
Trial IDNCT07441057 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Children aged 7–12 with a history of ischemic or hemorrhagic pediatric stroke and clinical upper limb motor impairment who can attend therapy and whose parents/guardians provide consent.

Probably not a fit

Children with severe cognitive or behavioral problems, uncontrolled seizures, recent intensive upper limb therapy, or orthopedic conditions limiting arm movement may not benefit or be eligible.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This interventional study delivers Comprehensive Hand Repetitive Intensive Strength Training (CHRIST), a high-repetition, strength-based, goal-oriented therapy targeting upper limb coordination and use in pediatric stroke survivors. Children aged 7–12 with clinical upper limb motor impairment receive structured therapy sessions and their manual ability is measured before and after the intervention using the ABILHAND-Kids questionnaire. Participants with recent intensive upper limb therapy, uncontrolled seizures, severe cognitive/behavioral impairments, or orthopedic limitations are excluded. The study is conducted at clinical sites that treat pediatric stroke patients in Mandi Bahāuddīn, Punjab Province.

Why it matters

Potential benefit: If successful, CHRIST could improve hand function and everyday arm use, helping affected children gain more independence in daily activities.

How similar studies have gone: High-repetition, goal-directed hand training has shown benefit in related populations such as pediatric cerebral palsy and adult stroke, but pediatric stroke–specific evidence remains limited.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Children aged 7 to 12 years diagnosed with pediatric ischemic or hemorrhagic stroke(21).

  * Clinical evidence of upper limb motor impairment following stroke.
  * Parent/guardian consent and child assent obtained.

Exclusion Criteria:

* Severe cognitive or behavioral impairments interfering with therapy.

  * Uncontrolled seizures or medical conditions contraindicating exercise.
  * Previous participation in intensive upper limb therapy within the last 3 months.
  * Orthopedic conditions (e.g., fractures, contractures) that limit upper limb movement.

Where it's running

  • Clinical settings having pediatric stroke patients.
    Mandi Bahāuddīn, Punjab Province, Pakistan
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.