CHRIST program to improve upper arm function in children after stroke
Official title: Effects of Comprehensive Hand Repetitive Intense Strength Training on Upper Limb Function in Children With Pediatric Stroke
Run by Riphah International University · NCT07441057 · Data updated 2026-11-12
We will try the CHRIST hand-strength and repetitive training program to see if it improves upper arm use in children aged 7–12 who had a stroke.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 7 Years to 12 Years |
| Sex | All |
| Enrollment | 15 (estimated) |
| Sponsor | Riphah International University Academic / other |
| Locations | 1 site (Mandi Bahāuddīn, Punjab Province) |
| Status | Recruiting |
| Started | February 4, 2026 |
| Main results expected | July 30, 2026 |
| Study ends | August 30, 2026 |
| Registry record updated | February 27, 2026 |
| Trial ID | NCT07441057 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Children aged 7–12 with a history of ischemic or hemorrhagic pediatric stroke and clinical upper limb motor impairment who can attend therapy and whose parents/guardians provide consent.
✕Probably not a fit
Children with severe cognitive or behavioral problems, uncontrolled seizures, recent intensive upper limb therapy, or orthopedic conditions limiting arm movement may not benefit or be eligible.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This interventional study delivers Comprehensive Hand Repetitive Intensive Strength Training (CHRIST), a high-repetition, strength-based, goal-oriented therapy targeting upper limb coordination and use in pediatric stroke survivors. Children aged 7–12 with clinical upper limb motor impairment receive structured therapy sessions and their manual ability is measured before and after the intervention using the ABILHAND-Kids questionnaire. Participants with recent intensive upper limb therapy, uncontrolled seizures, severe cognitive/behavioral impairments, or orthopedic limitations are excluded. The study is conducted at clinical sites that treat pediatric stroke patients in Mandi Bahāuddīn, Punjab Province.
Why it matters
Potential benefit: If successful, CHRIST could improve hand function and everyday arm use, helping affected children gain more independence in daily activities.
How similar studies have gone: High-repetition, goal-directed hand training has shown benefit in related populations such as pediatric cerebral palsy and adult stroke, but pediatric stroke–specific evidence remains limited.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Children aged 7 to 12 years diagnosed with pediatric ischemic or hemorrhagic stroke(21). * Clinical evidence of upper limb motor impairment following stroke. * Parent/guardian consent and child assent obtained. Exclusion Criteria: * Severe cognitive or behavioral impairments interfering with therapy. * Uncontrolled seizures or medical conditions contraindicating exercise. * Previous participation in intensive upper limb therapy within the last 3 months. * Orthopedic conditions (e.g., fractures, contractures) that limit upper limb movement.
Where it's running
-
Clinical settings having pediatric stroke patients.
Mandi Bahāuddīn, Punjab Province, Pakistan Recruiting
Study contacts
- Principal investigator: Mashar Hayat, MS — Riphah International University, Lahore
- Study coordinator: Imran Amjad, Phd
- Email: imran.amjad@riphah.edu.pk
- Phone: 03324390125
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Deep phenotyping to explore recovery in young adults after stroke
This project will test whether a detailed health and sample-collection approach (deep phenotyping) is practical and acceptable for people aged 18–55 who have had a stroke.
-
Stem cell therapy for chronic stroke recovery
This study is testing whether using a patient's own stem cells can help people with long-term stroke recovery feel better and improve their daily functioning.
-
AI-based tools to help diagnose, treat and predict stroke outcomes across multiple hospitals
This study tests AI-powered tools on real-world stroke patients to see if they can improve pre-hospital triage, diagnosis, and outcome prediction while data stay securely within each hospital.
-
Web-based therapy using action observation and mirror therapy for arm weakness after stroke
This trial tests whether a mobile telerehabilitation app delivering action observation therapy (AOT) alone or combined AOT with mirror therapy (AOT-MT) can improve upper limb function in people with subacute stroke.
-
Remote Ischaemic Conditioning for Fatigue After Stroke 2
Aat least 12 weeks after stroke, adults with post-stroke fatigue will try a simple hand-arm cuff treatment at home to see if it helps reduce fatigue.
-
Dual-task balance training plus computer-based cognitive training after stroke
In adults who recently had a stroke, the study tests whether adding computerized cognitive exercises to balance training improves balance and other recovery outcomes.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.