Chlorhexidine intervention for therapy dogs in hospitals

Clinical Trial of a Disinfectant Intervention in Therapy Dogs to Combat Hospital-associated Pathogens and Promote Sustainability of Animal-Assisted Visitation Programs

PHASE4 · Johns Hopkins Bloomberg School of Public Health · NCT04171817

This study tests if using a special cleaning solution on therapy dogs can help keep kids safe from germs while they interact with the dogs in hospitals.

Quick facts

PhasePHASE4
Study typeInterventional
Enrollment412 (estimated)
Ages3 Years to 17 Years
SexAll
SponsorJohns Hopkins Bloomberg School of Public Health (other)
Locations3 sites (Baltimore, Maryland and 2 other locations)
Trial IDNCT04171817 on ClinicalTrials.gov

What this trial studies

This clinical trial investigates the effectiveness of a chlorhexidine-based intervention aimed at therapy dogs involved in hospital-based Animal-Assisted visitation programs. The study will enroll children aged 3 to 17 years who will interact with therapy dogs over twelve sessions, assessing the risk of pathogen transmission and the impact of chlorhexidine on microbial communities. The trial includes an initial observational phase followed by a randomized controlled phase to evaluate the intervention's effects on patient outcomes such as blood pressure, heart rate, and self-reported pain and anxiety. The goal is to enhance the safety and sustainability of these beneficial programs.

Who should consider this trial

Good fit: Ideal candidates for this study are children aged 3 to 17 years who have been cleared by a physician to participate in animal-assisted visitation programs.

Not a fit: Patients who are allergic to dogs or have reported sensitivity to chlorhexidine products may not benefit from this study.

Why it matters

Potential benefit: If successful, this intervention could significantly reduce the risk of pathogen transmission during therapy dog sessions, enhancing patient safety and comfort.

How similar studies have performed: Previous studies have shown promise in using animal-assisted interventions in healthcare settings, but the specific chlorhexidine approach is novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Children between the ages of 3 and 17 years
* Cleared by physician to participate in a hospital-based animal-assisted visitation program session with any enrolled dog

Exclusion Criteria:

* Children who report sensitivity to chlorhexidine products
* Children who report allergy to dogs or sensitivity to dog allergen

Where this trial is running

Baltimore, Maryland and 2 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Methicillin-resistant Staphylococcus Aureus, Clostridium Difficile, Pseudomonas Aeruginosa, therapy dog, canine, animal assisted intervention, chlorhexidine, child

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.