Chitosan dressing for pulpotomy of immature permanent teeth
Efficacy of a Chitosan Dressing in Pulpotomy of Immature Permanent Teeth:Randomized Clinical Trial
NA · Minia University · NCT07323433
This trial tests whether placing a chitosan dressing during pulpotomy helps preserve the pulp and support continued root formation in children or adolescents with immature permanent front teeth damaged by caries or trauma.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 26 (estimated) |
| Ages | 7 Years to 15 Years |
| Sex | All |
| Sponsor | Minia University (other) |
| Locations | 1 site (Minya) |
| Trial ID | NCT07323433 on ClinicalTrials.gov |
What this trial studies
This is a single-center interventional study at Minia University Hospital testing a chitosan dressing as the wound-covering material after pulpotomy in immature maxillary anterior teeth with carious or traumatic pulp exposure. Clinicians remove the infected coronal pulp, achieve hemostasis, and place the chitosan dressing over the remaining healthy pulp, then restore the tooth and follow patients over time. Outcomes include clinical signs of success, radiographic evidence of continued root development and apex closure, and the effect of hemostasis on healing. Participants are followed for about one year to document healing and root formation.
Who should consider this trial
Good fit: Ideal candidates are patients with immature maxillary anterior teeth with pulp exposure from caries or trauma who are medically healthy (ASA class I) and can attend follow-up visits for about one year.
Not a fit: Patients with mature roots, signs of periapical inflammation, periodontal disease, vertical root fractures, previously started endodontic treatment, or systemic conditions affecting healing are unlikely to benefit from this approach.
Why it matters
Potential benefit: If successful, using a chitosan dressing could improve bleeding control and healing after pulpotomy and help immature teeth continue normal root development.
How similar studies have performed: Some laboratory and small clinical reports suggest chitosan can help control bleeding and support tissue healing, but evidence specifically for pulpotomy in immature permanent teeth is limited.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients with immature maxillary anterior teeth. * Patients with caries or traumatic exposed teeth . * Patients should be free from any systemic disease that may affect normal healing and predictable outcome class I ASA . * Patients who will agree to the consent and will commit to follow-up period. Exclusion Criteria: * Patients with mature roots. * Patients with any systemic disease that may affect normal healing. * Patients with signs of periapical inflammation. * Patients who could/would not participate in a 1-year follow-up. * Teeth with periodontal involvement. * Teeth with vertical root fractures. * Non- restorable teeth. * cases with previously initiated endodontic treatment.
Where this trial is running
Minya
- Minia University Hospital — Minya, Egypt (RECRUITING)
Study contacts
- Study coordinator: Salsabil Mohammed Naguib, MSc
- Email: salsabilnaguib@gmail.com
- Phone: +201026598006
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Caries,Dental