Chewing gum to speed bowel recovery after open gastrointestinal surgery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This randomized controlled trial will enroll 96 adults undergoing open gastrointestinal surgery and use block randomization to assign participants to a chewing-gum intervention or a control group. The intervention group will begin chewing glucose-containing gum six hours after surgery as a form of sham feeding. Primary outcomes include time to first bowel sounds, passage of flatus, and first defecation, with statistical comparisons between groups. The study aims to determine whether postoperative gum chewing shortens the duration of postoperative ileus and speeds recovery of gut motility.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age between 17 and 85 years.
* Patients of either gender.
* Undergoing open gastrointestinal surgical procedures (elective or emergency).
* Willing to participate and able to provide informed consent.

Exclusion Criteria:

* Patients with metabolic or endocrine disorders (diabetes mellitus, hypothyroidism, or hyperthyroidism).
* Patients with renal disease or electrolyte imbalance.
* Patients with chronic constipation or neuromuscular disorders.
* Patients with substance abuse or drug addiction.
* Patients receiving medications affecting gut motility (calcium channel blockers or antiepileptic drugs).
* Patients with dental prosthesis or undergoing laparoscopic gastrointestinal surgery.

Where it's running

• Khyber Teaching Hospital
  Peshawar, Kpk, Pakistan Recruiting

Study contacts

• Principal investigator: Dr Ali Raza, MBBS — Khyber Teaching Hospital
• Study coordinator: Dr Ali Raza, MBBS
• Email: dralicenna022@gmail.com
• Phone: +923452479895

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Bowel Sounds and Day-to-Day Recovery After Colorectal Cancer Surgery

  This study will test whether monitoring bowel sounds before and after colorectal cancer surgery can predict how quickly patients recover bowel function and resume eating.

  Recruiting Zhongnan Hospital · Wuhan, Hubei · NCT07705139

• Liposomal Bupivacaine TAP Block Plus Pain Control to Help Gut Recovery After Major Abdominal Surgery

  This trial tests whether adding liposomal bupivacaine TAP block to a sufentanil or oxycodone-based pain plan helps people recover gut function after major abdominal surgery.

  Recruiting Tianjin First Central Hospital · Tianjin, Tianjin Municipality · NCT07651722

• Restrictive versus liberal IV fluids during elective cesarean with spinal anesthesia

  This trial will test whether giving less versus more IV fluids during spinal anesthesia reduces nausea and speeds bowel recovery for women having an elective cesarean.

  Recruiting Nigde Omer Halisdemir University · Niğde, Merkez · NCT07440667

• Tegileridine for faster bowel recovery after abdominal surgery

  This trial tests if tegileridine, given after abdominal surgery, helps the gut start working sooner compared with morphine while both are used with a patient-controlled pump.

  Recruiting at 3 sites Phase 4 Xiangya Hospital of Central South University · Guangzhou, Guangdong and 2 other locations · NCT07412223

• Thread-embedding acupuncture to speed bowel recovery after colorectal cancer surgery.

  This trial will test whether adding thread embedding acupuncture (with electroacupuncture) helps adults recover bowel function faster after elective laparoscopic colorectal cancer surgery.

  Recruiting Northern Jiangsu People's Hospital · Yangzhou, Jiangsu · NCT07071987

• Simple bed exercises to reduce postoperative ileus after colorectal surgery

  This test tries simple bed exercises to see if they help adults who develop postoperative ileus after elective colorectal surgery get their bowels working sooner.

  Recruiting The University of Hong Kong · Hong Kong · NCT07014046

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.