Checking vitamin B12, folic acid, and vitamin D levels in women of reproductive age in Herzegovina
Assessment of Serum Concentrations of Vitamin B12, Folic Acid, and Vitamin D in Women of Reproductive Age to Determine Recommended Supplementation Doses in the Preconception Period and During Pregnancy
This project will test blood levels of vitamin B12, folic acid, and vitamin D in women aged 18–49 in Herzegovina to see if international supplement advice fits their needs.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 360 (estimated) |
| Ages | 18 Years to 49 Years |
| Sex | Female |
| Sponsor | University of Mostar Academic / other |
| Locations | 1 site (Mostar) |
| Trial ID | NCT07099586 on ClinicalTrials.gov |
What this trial studies
This is a cross-sectional observational study enrolling 360 women aged 18–49 between December 2024 and December 2025 at the University of Mostar to measure serum concentrations of vitamin B12, folic acid, and vitamin D. Participants will provide informed consent and a blood sample; serum levels will be measured using chemiluminescent microparticle immunoassays (CMIA) on the Abbott Alinity ci platform. Women with diabetes, epilepsy, oncological disease, inflammatory bowel disease, or recent supplementation with the studied vitamins are excluded. The goal is to document deficiency, adequacy, or excess in this population to inform locally adapted preconception and pregnancy supplementation guidance.
Who should consider this trial
Good fit: Ideal candidates are women aged 18–49 who can give informed consent, are resident or able to attend Mostar, and have not taken vitamin B12, folic acid, or vitamin D supplements in the past three months.
Not a fit: Women with diabetes, epilepsy, cancer, inflammatory bowel disease, or those who have used the relevant vitamin supplements in the past three months are excluded and will not benefit from this screening effort.
Why it matters
Potential benefit: If successful, the results could support locally tailored supplementation recommendations to reduce nutrition-related pregnancy risks.
How similar studies have performed: Similar population surveys measuring serum B12, folate, and vitamin D have been done elsewhere and have informed local supplement policies, but Herzegovina-specific data remain limited.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Women of reproductive age (18-49 years) * Informed consent obtained Exclusion Criteria: * diabetes (Type I or II) * epilepsy * oncological diseases, inflammatory bowel disease * supplementation with vitamin B12, folic acid, or vitamin D within the last 3 months
Where this trial is running
Mostar
- University Hospital Mostar — Mostar, Bosnia and Herzegovina (Recruiting)
Study contacts
- Study coordinator: Vajdana Tomić, professor, MD
- Email: vajdana.tomic@mef.sum.ba
- Phone: 063790012
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.