Check-up for sexual dysfunction in premenopausal breast cancer survivors on endocrine therapy

SEXCHECK - Sexual Dysfunction Check-up in Premenopausal Breast Cancer Survivors Taking Endocrine Therapy: A Cross-Sectional Study

Observational Candiolo Cancer Institute - IRCCS · NCT06458764

This study looks at how common sexual problems are in premenopausal women who have had early-stage breast cancer surgery and are on hormone therapy, and how these issues affect their quality of life.

Quick facts

Study typeObservational
Enrollment150 (estimated)
Ages18 Years to 55 Years
SexFemale
SponsorCandiolo Cancer Institute - IRCCS Academic / other
Locations1 site (Torino, TO)
Trial IDNCT06458764 on ClinicalTrials.gov

What this trial studies

This observational study aims to estimate the incidence of sexual dysfunction in premenopausal women who have undergone surgery for early-stage breast cancer and are currently receiving endocrine therapy. It will also assess the level of distress related to sexual dysfunction and its impact on quality of life. Additionally, the study will characterize the symptoms of sexual dysfunction and their correlation with different surgical and therapeutic approaches. Data collected will serve as a foundation for future randomized trials aimed at reducing sexual dysfunction in this population.

Who should consider this trial

Good fit: Ideal candidates are women aged 18 to 55 who have had surgery for early-stage breast cancer and are on endocrine therapy for at least three months.

Not a fit: Patients who have withdrawn consent or do not meet the age and treatment criteria may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved quality of life for breast cancer survivors by addressing sexual dysfunction.

How similar studies have performed: While this specific approach is observational, similar studies have indicated that addressing sexual dysfunction can significantly enhance the quality of life for breast cancer survivors.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* women aged ≥18 and ≤ 55
* who underwent surgery for early stage breast cancer
* taking endocrine therapy for at least 3 months
* providing an informed consent and completing the study questionnaires.

Exclusion Criteria:

* withdrawal of the informed consent, at any time

Where this trial is running

Torino, TO

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Breast Cancer FemaleSexual DysfunctionPremenopausal Breast Cancer
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.